PROTAC HDAC4 Degrader-1
PROTAC HDAC4 Degrader-1 (compound SCT-1) is a potent and selective PROTAC HDAC4 degrader. PROTAC HDAC4 Degrader-1 reduces HDAC4 protein level, induces S phase cell cycle arrest, and inhibits cell colony formation, thereby inhibiting proliferation of the tumor cells. PROTAC HDAC4 Degrader-1 exhibits efficacy in a H460 mouse model. PROTAC HDAC4 Degrader-1 can be used for cancer research, such as lung cancer.
(Pink: HDAC4 ligand (HY-10528); Blue: Cereblon ligand (HY-W834174); Black: linker (HY-W007587)).
For research use only. We do not sell to patients.
- CAS No.: 3036245-14-1
- Formula: C46H49F3N6O9
- Molecular Weight:886.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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HDAC4 |
Chemical Information
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CAS No. 3036245-14-1
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Molecular Weight 886.91
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Formula C46H49F3N6O9
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SMILES
O=C1C2=CC=C(N3CCN(CC3)C(CCCCCCCCOC4=C(C(N(C)C5=C4C(OC)=CC=C5)=O)C(N(C)C6=CC=C(C(F)(F)F)C=C6)=O)=O)C=C2C(N1C7C(NC(CC7)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC HDAC4 Degrader-1 Related Classifications
HY-179321 Related Classifications
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