1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. HDAC
  4. HDAC Inhibitors

HDAC Inhibitors

HDAC

HDAC1

HDAC2

HDAC3

HDAC4

HDAC5

HDAC6

HDAC7

HDAC8

HDAC9

HDAC10

HDAC11

HD1

HD2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

HDAC Inhibitors, Activators & Modulators
Product Name HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2 Purity
Trichostatin A
HDAC, IC50: 1.8 nM
                          99.58%
4-Phenylbutyric acid
HDAC
                          99.98%
Vorinostat  
HDAC1, ID50: 10 nM
 
HDAC3, ID50: 20 nM
                    99.90%
Valproic acid
HDAC, IC50: 0.5-2 mM
HDAC1, IC50: 400 μM
                        ≥98.0%
Sulforaphane
HDAC
                          99.11%
KR-39038          
HDAC5
                98.65%
Panobinostat lactate
HDAC
                         
HDAC6-IN-5
HDAC, IC50: 0.16 ± 0.0 μM
HDAC1, IC50: 0.09 ± 0.0 μM
HDAC2, IC50: 0.48 ± 0.0 μM
HDAC3, IC50: 0.33 ± 0. μM
HDAC4, IC50: 7.85 ± 0.6 μM
HDAC5, IC50: 7.19 ± 0.4 μM
HDAC6, IC50: 0.026 ± 0. μM
HDAC7, IC50: 9.13 ± 0.3 μM
 
HDAC9, IC50: 5.51 ± 0.0 μM
       
Panobinostat
HDAC
                          99.20%
Entinostat  
HDAC1, IC50: 243 nM
HDAC2, IC50: 453 nM
HDAC3, IC50: 248 nM
                    99.65%
Romidepsin  
HDAC1, IC50: 36 nM
HDAC2, IC50: 47 nM
 
HDAC4, IC50: 510 nM
 
HDAC6, IC50: 14000 nM
              99.98%
Tucidinostat  
HDAC1, IC50: 95 nM
HDAC2, IC50: 160 nM
HDAC3, IC50: 67 nM
       
HDAC8, IC50: 733 nM
 
HDAC10, IC50: 78 nM
HDAC11, IC50: 432 nM
    99.82%
RGFP966      
HDAC3, IC50: 80 nM
                    99.81%
Valproic acid sodium
HDAC, IC50: 0.5-2 mM
HDAC1, IC50: 400 μM
                        ≥98.0%
Ricolinostat  
HDAC1, IC50: 58 nM
HDAC2, IC50: 48 nM
HDAC3, IC50: 51 nM
HDAC4, IC50: 7000 nM
HDAC5, IC50: 5000 nM
HDAC6, IC50: 4.7 nM
HDAC7, IC50: 1400 nM
HDAC8, IC50: 100 nM
          99.83%
Sodium 4-phenylbutyrate
HDAC
                          99.96%
Belinostat
HDAC, IC50: 27 nM (Hela cell)
         
HDAC6, IC50: 82 nM
              99.94%
TMP195        
HDAC4, IC50: 111 nM
HDAC5, IC50: 106 nM
HDAC6, IC50: 47800 nM
HDAC7, IC50: 46 nM
HDAC8, IC50: 11700 nM
HDAC9, IC50: 9 nM
        99.19%
Tubastatin A  
HDAC1, IC50: 16400 nM
       
HDAC6, IC50: 15 nM
 
HDAC8, IC50: 854 nM
          98.10%
Mocetinostat  
HDAC1, IC50: 0.15 μM
HDAC2, IC50: 0.29 μM
HDAC3, IC50: 1.66 μM
             
HDAC11, IC50: 0.59 μM
    99.43%
Tasquinimod        
HDAC4, Kd: 10-30 nM
                  99.86%
TMP269        
HDAC4, IC50: 157 nM
HDAC5, IC50: 97 nM
HDAC6, IC50: 82000 nM
HDAC7, IC50: 43 nM
HDAC8, IC50: 42000 nM
HDAC9, IC50: 23 nM
        98.23%
FT895                      
HDAC11, IC50: 3 nM
    99.93%
ITSA-1
HDAC
                          ≥98.0%
Quisinostat  
HDAC1, IC50: 0.11 nM
HDAC2, IC50: 0.33 nM
HDAC3, IC50: 4.86 nM
HDAC4, IC50: 0.64 nM
HDAC5, IC50: 3.69 nM
HDAC6, IC50: 76.8 nM
HDAC7, IC50: 119 nM
HDAC8, IC50: 4.26 nM
HDAC9, IC50: 32.1 nM
HDAC10, IC50: 0.46 nM
HDAC11, IC50: 0.37 nM
    98.28%
Fimepinostat  
HDAC1, IC50: 1.7 nM
HDAC2, IC50: 5 nM
HDAC3, IC50: 1.8 nM
HDAC4, IC50: 409 nM
HDAC5, IC50: 674 nM
HDAC6, IC50: 27 nM
HDAC7, IC50: 426 nM
HDAC8, IC50: 191 nM
HDAC9, IC50: 554 nM
HDAC10, IC50: 2.8 nM
HDAC11, IC50: 5.4 nM
    99.95%
Santacruzamate A    
HDAC2, IC50: 119 pM
     
HDAC6, IC50: 434 nM
              99.32%
Tacedinaline  
HD1, IC50: 0.9 μM
HD2, IC50: 0.9 μM
HD3, IC50: 1.2 μM
                    99.55%
Tubacin  
HDAC1, IC50: 1.40 μM
HDAC2, IC50: 6.27 μM
HDAC3, IC50: 1.27 μM
HDAC4, IC50: 17.30 μM
HDAC5, IC50: 3.35 μM
HDAC6, IC50: 4 nM
HDAC7, IC50: 9.70 μM
HDAC8, IC50: 1.27 μM
HDAC9, IC50: 4.31 μM
HDAC10, IC50: 3.71 μM
HDAC11, IC50: 3.79 μM
   
PCI-34051  
HDAC1, IC50: 4 μM
       
HDAC6, IC50: 2.9 μM
 
HDAC8, IC50: 10 nM
 
HDAC10, IC50: 13 μM
      99.64%
Pracinostat  
HDAC1, IC50: 49 nM
HDAC2, IC50: 96 nM
HDAC3, IC50: 43 nM
HDAC4, IC50: 56 nM
HDAC5, IC50: 47 nM
HDAC6, IC50: 1008 nM
HDAC7, IC50: 137 nM
HDAC8, IC50: 140 nM
HDAC9, IC50: 70 nM
HDAC10, IC50: 40 nM
HDAC11, IC50: 93 nM
    99.82%
Tubastatin A Hydrochloride  
HDAC1, IC50: 16400 nM
       
HDAC6, IC50: 15 nM
 
HDAC8, IC50: 854 nM
          98.21%
SIS17                      
HDAC11, IC50: 0.83 μM
    99.65%
CUDC-101
HDAC, IC50: 4.4 nM
HDAC1, IC50: 4.5 nM
HDAC2, IC50: 12.6 nM
HDAC3, IC50: 9.1 nM
HDAC4, IC50: 13.2 nM
HDAC5, IC50: 11.4 nM
HDAC6, IC50: 5.1 nM
HDAC7, IC50: 373 nM
HDAC8, IC50: 79.8 nM
HDAC9, IC50: 67.2 nM
HDAC10, IC50: 26.1 nM
      99.19%
ACY-738  
HDAC1, IC50: 94 nM
HDAC2, IC50: 128 nM
HDAC3, IC50: 218 nM
   
HDAC6, IC50: 1.7 nM
              98.80%
Abexinostat  
HDAC1, Ki: 7 nM
HDAC2, Ki: 19 nM
HDAC3/SMRT, Ki: 8.2 nM
   
HDAC6, Ki: 17 nM
 
HDAC8, Ki: 280 nM
 
HDAC10, Ki: 24 nM
      98.61%
Dacinostat
HDAC, IC50: 32 nM
HDAC1, IC50: 9 nM
                        98.45%
Pyroxamide  
HDAC1, ID50: 100 nM
                        99.73%
BRD-6929  
HDAC1, IC50: 1 nM
HDAC2, IC50: 8 nM
HDAC3, IC50: 458 nM
                    99.04%
RG2833  
HDAC1, IC50: 60 nM
HDAC1, Ki: 32 nM
 
HDAC3, IC50: 50 nM
HDAC3, Ki: 5 nM
                    99.71%
CAY10603  
HDAC1, IC50: 271 nM
HDAC2, IC50: 252 nM
HDAC3, IC50: 0.42 nM
   
HDAC6, IC50: 0.002 nM
 
HDAC8, IC50: 6851 nM
 
HDAC10, IC50: 90.7 nM
      99.62%
MC1568
HDAC
                         
ACY-1083            
HDAC6, IC50: 3 nM
              99.43%
Givinostat hydrochloride monohydrate  
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
≥98.0%
Nexturastat A  
HDAC1, IC50: 3.02 μM
HDAC2, IC50: 6.92 μM
HDAC3, IC50: 6.68 μM
HDAC4, IC50: 9.39 μM
HDAC5, IC50: 11.7 μM
HDAC6, IC50: 5.02 nM
HDAC7, IC50: 4.46 μM
HDAC8, IC50: 0.954 μM
HDAC9, IC50: 6.72 μM
HDAC10, IC50: 7.57 μM
HDAC11, IC50: 5.14 μM
    99.03%
BRD 4354          
HDAC5, IC50: 0.85 μM
     
HDAC9, IC50: 1.88 μM
        98.29%
Domatinostat  
HDAC-1, IC50: 1.2 μM
HDAC-2, IC50: 1.12 μM
HDAC-3, IC50: 0.57 μM
 
HDAC-5, IC50: 11.3 μM
     
HDAC-9, IC50: 50 μM
HDAC-10, IC50: 21 μM
HDAC-11, IC50: 9.7 μM
    99.43%
J22352            
HDAC6, IC50: 4.7 nM
              98.72%
WT-161  
HDAC1, IC50: 8.35 nM
HDAC2, IC50: 15.4 nM
HDAC3, IC50: 51.6 nM
   
HDAC6, IC50: 0.4 nM
 
HDAC8, IC50: 1430 nM
          98.52%
HDAC8-IN-1                
HDAC8, IC50: 27.2 nM
          99.82%
Sinapinic acid
HDAC, IC50: 2.27 mM
                          99.77%
Scriptaid
HDAC
                          98.59%
ACY-957  
HDAC1, IC50: 7 nM
HDAC2, IC50: 18 nM
HDAC3, IC50: 1300 nM
                    99.87%
UF010  
HDAC1, IC50: 0.5 μM
HDAC2, IC50: 0.1 μM
HDAC3, IC50: 0.06 μM
   
HDAC6, IC50: 9.1 μM
 
HDAC8, IC50: 1.5 μM
 
HDAC10, IC50: 15.3 μM
HDAC11, IC50: 44.5 μM
    99.08%
CXD101  
HDAC1, IC50: 63 nM
HDAC2, IC50: 570 nM
HDAC3, IC50: 550 nM
                    99.71%
SW-100  
HDAC1, IC50: 5.23 μM
HDAC2, IC50: 32.8 μM
HDAC3, IC50: 29.5 μM
HDAC4, IC50: 10.9 μM
HDAC5, IC50: 4.07 μM
HDAC6, IC50: 2.3 nM
HDAC7, IC50: 4.55 μM
HDAC8, IC50: 3.72 μM
HDAC9, IC50: 3.46 μM
HDAC10, IC50: 26.2 μM
HDAC11, IC50: 5.72 μM
    99.59%
BRD3308  
HDAC1, IC50: 1260 nM
HDAC1, Ki: 5100 nM
HDAC2, IC50: 1340 nM
HDAC2, Ki: 6300 nM
HDAC3, IC50: 54 nM
HDAC3, Ki: 29 nM
                    98.07%
BML-210        
HDAC4:MEF2
                  98.06%
Bufexamac      
HDAC3, Kd app: 341 μM
   
HDAC6, Kd app: 10.7 μM
 
HDAC8, Kd app: 235 μM
 
HDAC10, Kd app: 12.3 μM
      ≥98.0%
Pimelic Diphenylamide 106  
HDAC1, IC50: 150 nM
HDAC2, IC50: 760 nM
HDAC3, IC50: 370 nM
       
HDAC8, IC50: 5000 nM
          98.39%
Citarinostat  
HDAC1, IC50: 35 nM
HDAC2, IC50: 45 nM
HDAC3, IC50: 46 nM
   
HDAC6, IC50: 2.6 nM
HDAC7, IC50: 7300 nM
HDAC8, IC50: 137 nM
          98.57%
CHDI-390576  
HDAC1, IC50: 39.7 μM
 
HDAC3, IC50: 25.8 μM
HDAC4, IC50: 54 nM
HDAC5, IC50: 60 nM
hHDAC6, IC50: 6.2 μM
HDAC7, IC50: 31 nM
HDAC8, IC50: 9.1 μM
hHDAC9, IC50: 50 nM
        99.42%
HDACs/mTOR Inhibitor 1  
HDAC1, IC50: 0.19 nM
       
HDAC6, IC50: 1.8 nM
              98.21%
Resminostat hydrochloride  
HDAC1, IC50: 42.5 nM
 
HDAC3, IC50: 50.1 nM
   
HDAC6, IC50: 71.8 nM
 
HDAC8, IC50: 877 nM
          99.12%
M344
HDAC, IC50: 100 nM
                          99.28%
TH34            
HDAC6, IC50: 4.6 μM
 
HDAC8, IC50: 1.9 μM
 
HDAC10, IC50: 7.7 μM
      98.41%
Elevenostat                      
HDAC11, IC50: 0.235 μM
   
EDO-S101  
HDAC1, IC50: 9 nM
HDAC2, IC50: 9 nM
HDAC3, IC50: 25 nM
   
HDAC6, IC50: 6 nM
 
HDAC8, IC50: 107 nM
 
HDAC10, IC50: 72 nM
      99.42%
PTACH  
HDAC1, IC50: 48 nM
   
HDAC4, IC50: 32 nM
 
HDAC6, IC50: 41 nM
              99.65%
ACY-775  
HDAC1, IC50: 2123 nM
HDAC2, IC50: 2570 nM
HDAC3, IC50: 11223 nM
   
HDAC6, IC50: 7.5 nM
              99.83%
Oxamflatin
HDAC, IC50: 15.7 nM
                          ≥98.0%
SR-4370  
HDAC1, IC50: 130 nM
HDAC2, IC50: 580 nM
HDAC3, IC50: 6 nM
   
HDAC6, IC50: 3400 nM
 
HDAC8, IC50: 2300 nM
          98.03%
JAK/HDAC-IN-1
HDAC, IC50: 2 nM
 
HDAC2, IC50: 14 nM
     
HDAC6, IC50: 120 nM
 
HDAC8, IC50: 2470 nM
          98.53%
Crotonoside      
HDAC3
   
HDAC6
              99.64%
Droxinostat      
HDAC3, IC50: 16.9 μM
   
HDAC6, IC50: 2.47 μM
 
HDAC8, IC50: 1.46 μM
          99.60%
KA2507            
HDAC6, IC50: 2.5 nM
 
HDAC8, IC50: 621
          98.09%
Suberoyl bis-hydroxamic acid  
HDAC1, IC50: 0.25 μM
 
HDAC3, IC50: 0.30 μM
                    ≥98.0%
BG45  
HDAC1, IC50: 2.0 μM
HDAC2, IC50: 2.2 μM
HDAC3, IC50: 0.289 μM
   
HDAC6, IC50: >20 μM
              99.95%
CG347B            
HDAC6
              98.93%
QTX125 TFA            
HDAC6
              98.97%
1-Naphthohydroxamic acid  
HDAC1, IC50: >100 μM
       
HDAC6, IC50: >100 μM
 
HDAC8, IC50: 14 μM
          ≥98.0%
Tefinostat
HDAC
                          98.08%
Splitomicin
Sir2p, IC50: 60 μM
                          98.42%
SS-208  
HDAC1, IC50: 1.39 μM
     
HDAC5, IC50: 6.91 μM
HDAC6, IC50: 12 nM
HDAC7, IC50: 8.34 μM
HDAC8, IC50: 1.23 μM
   
HDAC11, IC50: 5.12 μM
    98.13%
HPOB  
HDAC1, IC50: 2.9 μM
HDAC2, IC50: 4.4 μM
HDAC3/NCOR2, IC50: 1.7 μM
   
HDAC6, IC50: 0.056 μM
 
HDAC8, IC50: 2.8 μM
 
HDAC10, IC50: 3.0 μM
     
BRD73954    
HDAC2, IC50: 9 μM
     
HDAC6, IC50: 0.036 μM
 
HDAC8, IC50: 0.12 μM
          ≥98.0%
Domatinostat tosylate  
HDAC-1, IC50: 1.2 μM
HDAC-2, IC50: 1.12 μM
HDAC-3, IC50: 0.57 μM
 
HDAC-5, IC50: 11.3 μM
     
HDAC-9, IC50: 50 μM
HDAC-10, IC50: 21 μM
HDAC-11, IC50: 9.7 μM
    99.66%
MPT0G211            
HDAC6, IC50: 0.291 μM
              99.55%
NKL 22  
HDAC1, IC50: 0.199 μM
HDAC2, IC50: 1.59 μM
HDAC3, IC50: 0.069 μM
       
HDAC8, IC50: 5 μM
         
FNDR-20123
human HDAC, IC50: 3 nM
Plasmodium HDAC, IC50: 31 nM
HDAC1, IC50: 25 nM
HDAC2, IC50: 29 nM
HDAC3, IC50: 2 nM
   
HDAC6, IC50: 11 nM
 
HDAC8, IC50: 282 nM
          98.08%
CM-675  
HDAC1, IC50: 673 nM (30 min (time-dependent))
                        99.45%
Ivaltinostat formic
HDAC
                          99.36%
AES-135      
HDAC3, IC50: 654 nM
   
HDAC6, IC50: 190 nM
 
HDAC8, IC50: 1100 nM
   
HDAC11, IC50: 636 nM
    98.31%
BRD 4354 ditrifluoroacetate          
HDAC5, IC50: 0.85 μM
     
HDAC9, IC50: 1.88 μM
        98.06%
AES-350      
HDAC3, IC50: 187 nM
   
HDAC6, IC50: 24.4 nM
       
HDAC11, IC50: 245 nM
    98.02%
Ivaltinostat
HDAC
                         
HDAC-IN-3
HDAC
                          99.41%
Givinostat  
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pomiferin
HDAC, IC50: 1.05 μM
                         
SB-429201      
HDAC3, IC50: 1.5 μM
                    98.99%
QTX125            
HDAC6
             
Pivanex
HDAC
                         
Resminostat  
HDAC1, IC50: 42.5 nM
 
HDAC3, IC50: 50.1 nM
   
HDAC6, IC50: 71.8 nM
 
HDAC8, IC50: 877 nM
         
Quisinostat dihydrochloride  
HDAC1, IC50: 0.11 nM
HDAC2, IC50: 0.33 nM
HDAC3, IC50: 4.86 nM
 
HDAC5, IC50: 3.69 nM
HDAC6, IC50: 76.8 nM
HDAC7, IC50: 119 nM
HDAC8, IC50: 4.26 nM
HDAC9, IC50: 32.1 nM
HDAC10, IC50: 0.46 nM
HDAC11, IC50: 0.37 nM
   
MPT0E028  
HDAC1, IC50: 53.0 nM
HDAC2, IC50: 106.2 nM
     
HDAC6, IC50: 29.5 nM
 
HDAC8, IC50: 2532.6 nM
          99.63%
IDO1 and HDAC1 Inhibitor  
HDAC1, IC50: 66.5 nM
                       
SHP2/HDAC-IN-1  
HDAC1, IC50: 25 nM
HDAC2, IC50: 79 nM
HDAC3, IC50: 233 nM
   
HDAC6, IC50: 27 nM
             
PI3K/HDAC-IN-1  
HDAC1, IC50: 1.4 nM
HDAC2, IC50: 3.0 nM
     
HDAC6, IC50: 6.6 nM
 
HDAC8, IC50: 18 nM
         
GEM144                      
HDAC11, IC50: 8.23 μM
   
LSD1/HDAC6-IN-1            
HDAC6
             
FNDR-20123 free base
human HDAC, IC50: 3 nM
Plasmodium HDAC, IC50: 31 nM
HDAC1, IC50: 25 nM
HDAC2, IC50: 29 nM
HDAC3, IC50: 2 nM
   
HDAC6, IC50: 11 nM
 
HDAC8, IC50: 282 nM
         
MPT0G211 mesylate            
HDAC6, IC50: 0.291 μM
             
HDAC1/2 and CDK2-IN-1  
HDAC1, IC50: 70.7 nM
HDAC2, IC50: 23.1 nM
                     
Purinostat mesylate  
HDAC1, IC50: 0.81 nM
HDAC2, IC50: 1.4 nM
HDAC3, IC50: 1.7 nM
HDAC4, IC50: 1072 nM
HDAC5, IC50: 426 nM
HDAC6, IC50: 11.5 nM
HDAC7, IC50: 590 nM
HDAC8, IC50: 3.8 nM
HDAC9, IC50: 622 nM
HDAC10, IC50: 1.1 nM
HDAC11, IC50: 3349 nM
   
HDAC6-IN-6
HDAC, IC50: 0.55 ± 0.0 μM
HDAC1, IC50: 0.34 ± 0.0 μM
HDAC2, IC50: 1.57 ± 0.0 μM
HDAC3, IC50: 1.22 ± 0.0 μM
HDAC4, IC50: 2.24 ± 0.0 μM
HDAC5, IC50: 0.85 ± 0.0 μM
HDAC6, IC50: 0.025 ± 0. μM
HDAC7, IC50: 0.65 ± 0.0 μM
 
HDAC9, IC50: 0.57 ± 0.0 μM
       
HDAC6/8/BRPF1-IN-1  
HDAC1, IC50: 797 nM
       
HDAC6, IC50: 344 nM
 
HDAC8, IC50: 908 nM
         
MC1742  
HDAC1, IC50: 0.1 μM
HDAC2, IC50: 0.11 μM
HDAC3, IC50: 0.02 μM
   
HDAC6, IC50: 0.007 μM
 
HDAC8, IC50: 0.61 μM
 
HDAC10, IC50: 0.04 μM
HDAC11, IC50: 0.1 μM
   
HPB  
HDAC1, IC50: 1130 nM
       
HDAC6, IC50: 31 nM
             
HDAC3-IN-1  
HDAC1, IC50: 36.4 ± 0.2 nM
HDAC2, IC50: 89.9 ± 0.7 nM
HDAC3, IC50: 5.96 ± 0.0 nM
                   
TH-6  
HDAC1, IC50: 0.115 μM
HDAC2, IC50: 0.135 μM
HDAC3, IC50: 0.242 μM
   
HDAC6, IC50: 0.138 μM
 
HDAC8, IC50: 2.120 μM
         
HDAC6-IN-9  
HDAC1, IC50: 11.8 nM
 
HDAC3, IC50: 15.2 nM
   
HDAC6, IC50: 4.2 nM
 
HDAC8, IC50: 139.6 nM
 
HDAC10, IC50: 21.3 nM
     
HDAC-IN-45  
HDAC1, IC50: 0.108 μM
HDAC2, IC50: 0.585 μM
HDAC3, IC50: 0.563 μM μM
   
HDAC6, IC50: ﹥10 μM
 
HDAC8, IC50: 6.81 μM
         
HDAC2-IN-1  
HDAC1, IC50: 1.61 μM
HDAC2, IC50: 0.5 μM
         
HDAC8, IC50: 0.98 μM
         
HDAC-IN-36  
HDAC1, IC50: 86.93 nM
HDAC2, IC50: 97.32 nM
HDAC3, IC50: 79.17 nM
HDAC4, IC50: >1000 nM
HDAC5, IC50: >1000 nM
HDAC6, IC50: 11.68 nM
HDAC7, IC50: >1000 nM
HDAC8, IC50: 378.2 nM
HDAC9, IC50: >1000 nM
HDAC10, IC50: 13.24 nM
HDAC11, IC50: >1000 nM
   
HDAC-IN-39  
HDAC1, IC50: 1.07 μM
HDAC2, IC50: 1.47 μM
HDAC3, IC50: 2.27 μM
       
HDAC8, IC50: >10 μM
         
NMDAR/HDAC-IN-1  
HDAC1, IC50: 2.67 μM
HDAC2, IC50: 8.00 μM
HDAC3, IC50: 2.21 μM
   
HDAC6, IC50: 0.18 μM
 
HDAC8, IC50: 0.62 μM
         
PTG-0861            
HDAC6, IC50: 5.92 nM
             
HDAC10-IN-2            
hHDAC6, IC50: 3700 ± 450 nM
 
hHDAC8, IC50: 470 ± 70 nM
 
HDAC10, IC50: 20 ± 2 nM
     
PHD2/HDACs-IN-1  
HDAC1, IC50: 19.75 μM
HDAC2, IC50: 26.60 μM
     
HDAC6, IC50: 15.98 μM
             
Valproic acid (sodium)(2:1)
HDAC, IC50: 0.5-2 mM
HDAC1, IC50: 400 μM
                       
HDAC8-IN-2  
hHDAC1, IC50: 18.51 ± 1. μM
       
hHDAC6, IC50: 0.29 ± 0.0 μM
 
hHDAC8, IC50: 0.32 ± 0.0 μM
         
HDAC8-IN-3  
HDAC1, IC50: >50 μM
HDAC2, IC50: 41 μM
HDAC3, IC50: >50 μM
HDAC4, IC50: >50 μM
HDAC5, IC50: >50 μM
HDAC6, IC50: 17 μM
 
HDAC8, IC50: 9.3 μM
HDAC8, IC50: >50 μM
         
PI3K/HDAC-IN-2  
HDAC1, IC50: 1.3 nM
HDAC2, IC50: 3.4 nM
 
HDAC4, IC50: 972 nM
 
HDAC6, IC50: 17 nM
 
HDAC8, IC50: 12 nM
         
mTOR/HDAC-IN-1  
HDAC1, IC50: 0.91 nM
       
HDAC6, IC50: 86 nM
 
HDAC8, IC50: 27 nM
         
HDAC1-IN-3  
HDAC1, IC50: 2.2 nM
HDAC2, IC50: 5.1 nM
HDAC3, IC50: 5.2 nM
   
HDAC6, IC50: 85.5 nM
 
HDAC8, IC50: 29.9 nM
         
HDAC6/HSP90-IN-2  
HDAC1, IC50: 654.5 nM
 
HDAC3, IC50: 1539 nM
   
HDAC6, IC50: 106 nM
HDAC7, IC50: 1691 nM
           
HDAC6-IN-10  
HDAC1, IC50: 8020 nM
   
HDAC4, IC50: 5620 nM
HDAC5, IC50: 4370 nM
HDAC6, IC50: 0.73 nM
HDAC7, IC50: 752 nM
HDAC8, IC50: 513 nM
HDAC9, IC50: 2560 nM
HDAC10, IC50: 105 nM
HDAC11, IC50: 1800 nM
   
HDAC-IN-35  
HDAC1, IC50: 7.23 μM
       
HDAC6, IC50: 0.166 μM
 
HDAC8, IC50: 1.99 μM
         
PDE5/HDAC-IN-1  
HDAC1, IC50: 2.45 μM
       
HDAC6, IC50: 0.11 μM
 
HDAC8, IC50: 0.12 μM
         
HDAC-IN-38  
HDAC1, IC50: 3.82 μM
HDAC2, IC50: 6.62 μM
HDAC3, IC50: 2.86 μM
 
HDAC5, IC50: 6.27 μM
HDAC6, IC50: 1.27 μM
 
HDAC8, IC50: 0.533 μM
         
HDAC-IN-43  
HDAC1, IC50: 82 nM
HDAC2, IC50: 358 nM
HDAC3, IC50: 45 nM
   
HDAC6, IC50: 24 nM
 
HDAC8, IC50: 1441 nM
 
HDAC10, IC50: 182 nM
HDAC11, IC50: 9061 nM
   
Chlamydocin
HDAC, IC50: 1.3 nM
                         
CDK/HDAC-IN-2  
HDAC1, IC50: 6.4 nM
HDAC2, IC50: 0.25 nM
HDAC3, IC50: 45 nM
   
HDAC6, IC50: >1000 nM
 
HDAC8, IC50: >1000 nM
         
HDAC6-IN-11            
HDAC6, IC50: 20.7 nM
 
HDAC8, IC50: 7750 nM
         
HDAC3/6-IN-2  
HDAC1, IC50: 2.512 μM
HDAC2, IC50: 4.830 μM
HDAC3, IC50: 0.635 μM
   
HDAC6, IC50: 0.368 μM
             
HDAC1/MAO-B-IN-1  
HDAC1, IC50: 21.4 nM
                       
HDAC-IN-41  
HDAC1, IC50: 0.62 μM
HDAC2, IC50: 1.46 μM
HDAC3, IC50: 0.62 μM
                   
Tucidinostat-d4  
HDAC1, IC50: 95 nM
HDAC2, IC50: 160 nM
HDAC3, IC50: 67 nM
           
HDAC10, IC50: 78 nM
     
HDAC-IN-42  
HDAC1, IC50: 0.19 μM
       
HDAC6, IC50: 4.98 μM
             
HDAC-IN-9  
HDAC1, IC50: 6.8 μM
HDAC2, IC50: 0.06 μM
     
HDAC6, IC50: 0.12 μM
 
HDAC8, IC50: 8.5 μM
         
Top/HDAC-IN-2  
HDAC1, IC50: 0.004 μM
HDAC2, IC50: 0.005 μM
HDAC3, IC50: 1.10 μM
   
HDAC6, IC50: 0.15 μM
 
HDAC8, IC50: 4.5 μM
         
HDAC8/BRPF1-IN-1                
hHDAC8, IC50: 443 nM
         
HDAC-IN-40    
HDAC2, Ki: 60 nM
 
HDAC4, Ki: 49200 μM
 
HDAC6, Ki: 30 nM
 
HDAC8, Ki: 5690 nM
          98.71%
HDAC/Top-IN-1  
HDAC1, IC50: 34 nM
HDAC2, IC50: 140 nM
HDAC3, IC50: 59 nM
   
HDAC6, IC50: 89 nM
 
HDAC8, IC50: 9.8 μM
         
HDAC3-IN-T247  
HDAC1, IC50: 19 μM
 
HDAC3, IC50: 0.24 μM
HDAC4, IC50: >100 μM
 
HDAC6, IC50: >100 μM
 
HDAC8, IC50: >100 μM
         
Snail/HDAC-IN-1  
HDAC1, IC50: 0.405 μM
                       
A2AAR/HDAC-IN-1  
HDAC1, IC50: 145.3 ± 12 nM
HDAC2, IC50: 240.2 ± 19 nM
HDAC3, IC50: 443.5 ± 27 nM
   
HDAC6, IC50: >10000 nM
 
HDAC8, IC50: >10000 nM
         
HD-TAC7  
HDAC1, IC50: 3.6 μM
HDAC2, IC50: 4.2 μM
HDAC3, IC50: 1.1 μM
                   
HDAC-IN-46  
HDAC1, IC50: 0.21 μM
       
HDAC6, IC50: 0.021 μM
             
NCC-149                
HDAC8
         
HDAC/HSP90-IN-3
HDAC, IC50: 0.91 μM (fungal HDACs)
human HDAC, IC50: 3.0 μM (human HDACs)
                         
MIR002                      
HDAC11, IC50: 6.09 μM
   
KH-259  
HDAC1, IC50: 6.7 ± 0.14 μM
   
HDAC4, IC50: 12.3 ± 0.4 μM
 
HDAC6, IC50: 0.26 ± 0.2 μM
             
NN-390  
HDAC1, IC50: >5 μM
HDAC2, IC50: >5 μM
HDAC3, IC50: >1 μM
   
HDAC6, IC50: 9.8 nM
 
HDAC8, IC50: >1 μM
   
HDAC11, IC50: >1 μM
   
G4/HDAC-IN-1  
HDAC1, IC50: 1.26 μM
   
HDAC4, IC50: 2.64 μM
 
HDAC6, IC50: 0.65 μM
 
HDAC8, IC50: 0.03 μM
   
HDAC11, IC50: 1.38 μM
   
HDAC6/HSP90-IN-1  
HDAC1, IC50: 1878 nM
 
HDAC3, IC50: 1312 nM
   
HDAC6, IC50: 4.32 nM
 
HDAC8, IC50: 3720 nM
         
HDAC-IN-37  
HDAC1, IC50: 55.1 nM
 
HDAC3, IC50: 1.24 μM
   
HDAC6, IC50: 34.2 μM
 
HDAC8, IC50: 0.948 μM
         
c-Met/HDAC-IN-3  
HDAC1, IC50: 26.97 nM
                       
PARP-1/HDAC-IN-1    
HDAC2, IC50: 42130 nM
HDAC3, IC50: 7220 nM
   
HDAC6, IC50: 510 nM
             
HDAC6-IN-4  
HDAC1, IC50: 3604 nM
HDAC2, IC50: 172 nM
HDAC3, IC50: 46 nM
   
HDAC6, IC50: 23 nM
 
HDAC8, IC50: 2175 nM
         
HDAC-IN-31  
HDAC1, IC50: 84.90 nM
HDAC2, IC50: 168.0 nM
HDAC3, IC50: 442.7 nM
       
HDAC8, IC50: >10000 nM
         
mTOR/HDAC6-IN-1            
HDAC6, IC50: 56 nM
             
AChE/HDAC-IN-1
HDAC, IC50: 0.23 nM
                         
c-Met/HDAC-IN-2  
HDAC1, IC50: 18.49 nM
                       
PIM-1/HDAC-IN-1
HDAC, IC50: 65.94 ± 3. nM
HDAC1, IC50: 63.65 ± 3. nM
HDAC2, IC50: 132.62 nM
HDAC3, IC50: 323.02 nM
HDAC4, IC50: 265.47 nM
 
HDAC6, IC50: 62.39 ± 3. nM
 
HDAC8, IC50: 406.66 nM
         
Tubulin/HDAC-IN-1            
HDAC6, IC50: 1 μM
 
HDAC8, IC50: 150 nM
   
HDAC11, IC50: 1.9 μM
   
Coumarin-SAHA                
HDAC8
         
SAHA-OH  
HDAC1, IC50: 237 nM
HDAC2, IC50: 399 nM
HDAC3, IC50: 359 nM
   
HDAC6, IC50: 23 nM
 
HDAC8, IC50: 1070 nM
         
HDAC-IN-30  
HDAC1, IC50: 13.4 nM
HDAC2, IC50: 28.0 nM
HDAC3, IC50: 9.18 nM
   
HDAC6, IC50: 42.7 nM
 
HDAC8, IC50: 131 nM
         
BRD6688    
HDAC2
                     
HDAC-IN-34  
HDAC1, IC50: 0.022 ± 0. μM
       
HDAC6, IC50: 0.45 ± 0.0 μM
             
HDAC1-IN-5  
HDAC1, IC50: 15 nM
       
HDAC6, IC50: 20 nM
             
HDAC6-IN-13  
HDAC1, IC50: 1.53 μM
HDAC2, IC50: 2.06 μM
HDAC3, IC50: 1.03 μM
   
HDAC6, IC50: 0.019 μM
             
Crebinostat  
HDAC1, IC50: 0.7 nM
HDAC2, IC50: 1.0 nM
HDAC3, IC50: 2.0 nM
   
HDAC6, IC50: 9.3 nM
             
HDAC-IN-47  
HDAC1, IC50: 19.75 nM
HDAC2, IC50: 57.8 nM
HDAC3, IC50: 40.27 nM
   
HDAC6, IC50: 5.63 nM
 
HDAC8, IC50: 302.73 nM
         
HDAC10-IN-1            
hHDAC6, IC50: 2420 ± 530 nM
 
hHDAC8, IC50: 920 ± 170 nM
 
HDAC10, IC50: 58 ± 10 nM
     
1-Alaninechlamydocin
HDAC, IC50: 6.4 nM
                         
HDAC1/6-IN-1  
HDAC1, IC50: 89 nM
       
HDAC6, IC50: 13 nM
             
Givinostat hydrochloride  
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC3, IC50: 157 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
CRA-026440  
HDAC1, Ki: 4 nM
HDAC2, Ki: 14 nM
HDAC3, Ki: 11 nM
   
HDAC6, Ki: 15 nM
 
HDAC8, Ki: 7 nM
 
HDAC10, Ki: 20 nM
     
BRD4884  
HDAC1, IC50: 29 nM
HDAC2, IC50: 62 nM
HDAC3, IC50: 1.09 μM