1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. HDAC
  4. HDAC11 Isoform

HDAC11

 

HDAC11 Related Products (32):

Cat. No. Product Name Effect Purity
  • HY-10221
    Vorinostat
    Inhibitor 99.90%
    Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively.
  • HY-109015
    Tucidinostat
    Inhibitor 99.82%
    Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9.
  • HY-12164
    Mocetinostat
    Inhibitor 99.43%
    Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively.
  • HY-112285
    FT895
    Inhibitor 99.93%
    FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM.
  • HY-15433
    Quisinostat
    Inhibitor 98.28%
    Quisinostat (JNJ-26481585) is a potent, second-generation and orally active pan-HDAC inhibitor (HDACi), with IC50 values ranging from 0.11 nM to 0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11.
  • HY-150109
    Purinostat mesylate
    Inhibitor
    Purinostat mesylate is a selective inhibitor of HDAC.
  • HY-150595
    HDAC6-IN-10
    Inhibitor
    HDAC6-IN-10 is a highly selective HDAC6 inhibitor with the IC50 of 0.73 nM.
  • HY-147966
    HDAC-IN-43
    Inhibitor
    HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82, 45, and 24 nM, respectively.
  • HY-13522
    Fimepinostat
    Inhibitor 99.95%
    Fimepinostat (CUDC-907) potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively.
  • HY-13428
    Tubacin
    Inhibitor
    Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1.
  • HY-128918
    SIS17
    Inhibitor 99.65%
    SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.
  • HY-13322
    Pracinostat
    Inhibitor 99.82%
    Pracinostat is a potent histone deacetylase (HDAC) inhibitor, with IC50s of 40-140 nM, used for cancer research.
  • HY-16699
    Nexturastat A
    Inhibitor 99.03%
    Nexturastat A is a potent, selective HDAC6 inhibitor.
  • HY-14842B
    Givinostat hydrochloride monohydrate
    Inhibitor ≥98.0%
    Givinostat hydrochloride monohydrate (ITF-2357 hydrochloride monohydrate) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
  • HY-16012A
    Domatinostat
    Inhibitor 99.08%
    Domatinostat (4SC-202 free base) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively.
  • HY-18976
    UF010
    Inhibitor 99.08%
    UF010 is a potent and selective HDAC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.
  • HY-115475
    SW-100
    Inhibitor 99.59%
    SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes.
  • HY-145757
    Elevenostat
    Inhibitor
    Elevenostat (JB3-22) is a selective HDAC11 inhibitor (IC50=0.235 µM).
  • HY-126330
    SS-208
    Inhibitor 98.13%
    SS-208 is a selective HDAC6 inhibitor, with an IC50 of 12 nM.
  • HY-16012
    Domatinostat tosylate
    Inhibitor 99.66%
    Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively.