2126744-35-0
2126744-35-0
Chemical Structure
SW-100
- CAS No.: 2126744-35-0
- Formula:C17H17ClN2O2
- Molecular Weight:316.78
IUPAC Name: 4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxybenzamide
InChIKey: MNAYBFFSFQRSIT-UHFFFAOYSA-N
SMILES: O=C(NO)C1=CC=C(CN2CCCC3=C2C=CC(Cl)=C3)C=C1
Biological Activity: SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the blood-brain-barrier[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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SW-100 | 99.93% | SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the blood-brain-barrier. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.66
HY-149966PB131 -
Similarity Score 0.65
HY-181942HDAC6-IN-77 -
Similarity Score 0.64
HY-145845HDAC1/MAO-B-IN-1 -
Similarity Score 0.62
HY-153017HIF-1 inhibitor-4 -
Similarity Score 0.62
HY-42476Tolvaptan Impurity -
Similarity Score 0.61
HY-108161LF 1695 -
Similarity Score 0.60
HY-147731HDAC6-IN-9 -
Similarity Score 0.60
HY-123976MPT0G211 -
Similarity Score 0.60
HY-111818TH34 -
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