2374313-54-7
2374313-54-7
Chemical Structure
SIS17
- CAS No.: 2374313-54-7
- Formula:C21H38N2OS
- Molecular Weight:366.60
IUPAC Name: N'-hexadecylthiophene-2-carbohydrazide
InChIKey: HSHXDCVZWHOWCS-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CS1)NNCCCCCCCCCCCCCCCC
Biological Activity: SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. SIS17 inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs[1].
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SIS17 | 99.43% | SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. SIS17 inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. | ||||||||||||||||||||
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References
Keywords
