1403783-31-2
1403783-31-2
Chemical Structure
Nexturastat A
- CAS No.: 1403783-31-2
- Formula:C19H23N3O3
- Molecular Weight:341.40
IUPAC Name: 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide
InChIKey: JZWXMCPARMXZQV-UHFFFAOYSA-N
SMILES: O=C(NO)C1=CC=C(CN(CCCC)C(NC2=CC=CC=C2)=O)C=C1
Biological Activity: Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nexturastat A | 98.69% | Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM). | ||||||||||||||||||||
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References
- [1]. Bergman JA, et al. Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. J Med Chem. 2012 Nov 26;55(22):9891-9. [Content Brief]
- [2]. Xiaoyang Sun, et al. The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma. Biosci Rep. 2019 Mar 22;39(3):BSR20181916. [Content Brief]
