1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC
  3. BML-210

BML-210 

Cat. No.: HY-19350 Purity: 96.00%
Handling Instructions

BML-210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized.

For research use only. We do not sell to patients.

BML-210 Chemical Structure

BML-210 Chemical Structure

CAS No. : 537034-17-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 106 In-stock
Estimated Time of Arrival: December 31
5 mg USD 96 In-stock
Estimated Time of Arrival: December 31
10 mg USD 144 In-stock
Estimated Time of Arrival: December 31
50 mg USD 600 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

BML-210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized. IC50 value: 5 μM[1] Target: HDAC4 In vitro: Cell cycle analysis indicated that HeLa cell treatment with 20 and 30 μM concentration of BML-210 increased the proportion of cells in G0/G1 phase, and caused accumulation in subG1, indicating that the cells are undergoing apoptosis[2]. BML-210 inhibits the growth of NB4 cells in dose- and time-dependent manner[3]. In vivo:

IC50 & Target[1]

HDAC4:MEF2

 

Molecular Weight

339.43

Formula

C₂₀H₂₅N₃O₂

CAS No.

537034-17-6

SMILES

O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (88.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9461 mL 14.7306 mL 29.4612 mL
5 mM 0.5892 mL 2.9461 mL 5.8922 mL
10 mM 0.2946 mL 1.4731 mL 2.9461 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
BML-210
Cat. No.:
HY-19350
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