17364-16-8
17364-16-8
Chemical Structure
1-Palmitoyl-sn-glycero-3-phosphocholine
Synonym(s): 16:0 Lyso PC
- CAS No.: 17364-16-8
- Formula:C24H50NO7P
- Molecular Weight:495.63
IUPAC Name: (R)-2-hydroxy-3-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
InChIKey: ASWBNKHCZGQVJV-HSZRJFAPSA-N
SMILES: CCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Biological Activity: 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine | 99.92% | 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | ||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine (Standard) | ≥98% | 1-Palmitoyl-sn-glycero-3-phosphocholine (Standard) (16:0 Lyso PC (Standard)) is the analytical standard of 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). This product is intended for research and analytical applications. 1-Palmitoyl-sn-glycero-3-phosphocholine is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | ||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine-d31 | 99.94% | 1-Palmitoyl-sn-glycero-3-phosphocholine-d31 (16:0 Lyso PC-d31) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | ||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 | 95.0% | 1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1 (16:0 Lyso PC-d9-1) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | ||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine-d9 | 1-Palmitoyl-sn-glycero-3-phosphocholine-d9 (16:0 Lyso PC-d9) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | |||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine-d49 | 99% | 1-Palmitoyl-sn-glycero-3-phosphocholine-d49 (16:0 Lyso PC-d49) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis. | ||||||||||||||||||||
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1-Palmitoyl-sn-glycero-3-phosphocholine-d3 | 1-Palmitoyl-sn-glycero-3-phosphocholine-d3 is a deuterated phosphocholine. | |||||||||||||||||||||
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References
- [1]. Choi S, et al. Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells. Cell Physiol Biochem. 2010;25(2-3):233-40. [Content Brief]
- [2]. Qin X, et al. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation. Cell Immunol. 2014 May-Jun;289(1-2):185-90. [Content Brief]
- [3]. Hasegawa H, et al. Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production. Biochem Biophys Res Commun. 2011 Nov 25;415(3):526-31. [Content Brief]
- [4]. Yan JJ, et al. Therapeutic effects of lysophosphatidylcholine in experimental sepsis. Nat Med. 2004 Feb;10(2):161-7. [Content Brief]
Keywords
- 1-Palmitoyl-sn-glycero-3-phosphocholine
- 1-Palmitoyl-sn-glycero-3-phosphocholine (Standard)
- 1-Palmitoyl-sn-glycero-3-phosphocholine-d31
- 1-Palmitoyl-sn-glycero-3-phosphocholine-d9-1
- 1-Palmitoyl-sn-glycero-3-phosphocholine-d9
- 1-Palmitoyl-sn-glycero-3-phosphocholine-d49
- 1-Palmitoyl-sn-glycero-3-phosphocholine-d3
