(Z)-(R)-3-(Phosphonooxy)propane-1,2-diyl dioleate sodium salt
Based on 2 publication(s) in Google Scholar
1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA sodium salt) is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes.
For research use only. We do not sell to patients.
- Purity : 99.44%
- CAS No.: 108392-02-5
- Formula: C39H72NaO8P
- Molecular Weight:722.95
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) (Z)-(R)-3-(Phosphonooxy)propane-1,2-diyl dioleate sodium salt
More
Biological Activity
Description
In Vitro
1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (DOPA) can be used to prepare Zol-Ca complex nanoparticle formulations to improve the delivery of Zol in mouse tumor models and enhance its distribution[1].
1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (DOPA) can be used in combination with a fluorescent dye, calcium phosphate, to enhance its adsorption on the bacterial surface, deliver fluorescent groups and target the biofilm of S. aureus to enhance its biofilm staining ability[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 108392-02-5
-
Appearance Solid
-
Molecular Weight 722.95
-
Formula C39H72NaO8P
-
Color Colorless to off-white
-
SMILES
CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)(O[Na])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
J Am Chem Soc
Safe and Highly Efficient Lipid-Pro-Dexamethasone Nanoparticles for mRNA Delivery and Base Editing. [Abstract]2026 Mar 11;148(9):10225-10240. PMID: 41733506 -
J Phys Chem B
Studying the Signaling Mechanism of Neuropilin-1's Intracellular Disorder Region via Conformational Mining and Dynamic Interaction Characterization. [Abstract]2025 Mar 6;129(9):2392-2401. PMID: 39993015
Solvent & Solubility
In Vitro:
Methanol : 10 mg/mL (13.83 mM; Need ultrasonic)
DMSO : 1.25 mg/mL (1.73 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : < 1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Xu Li, et al. Reverse Microemulsion-Based Synthesis of (Bis)phosphonate-Metal Materials with Controllable Physical Properties: An Example Using Zoledronic Acid-Calcium Complexes. [Content Brief]
[2]. Ignacio Rivero Berti, et al. Delivery of fluorophores by calcium phosphate-coated nanoliposomes and interaction with Staphylococcus aureus biofilms. Colloids Surf B Biointerfaces. 2016 Jun 1;142:214-222. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Methanol | 1 mM | 1.3832 mL | 6.9161 mL | 13.8322 mL | 34.5805 mL |
| Methanol | 5 mM | 0.2766 mL | 1.3832 mL | 2.7664 mL | 6.9161 mL |
| 10 mM | 0.1383 mL | 0.6916 mL | 1.3832 mL | 3.4581 mL |