2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. CDNF/MANF family
  6. ARMET/MANF

ARMET/MANF

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Cat. No. Product Name / Synonyms Species Source
  • HY-P71940A
    ARMET/MANF Protein, Human (His)

    Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET

    		Human E. coli
    ARMET/MANF proteins critically support the survival of dopaminergic neurons in the ventral midbrain and contribute to neuronal homeostasis. It modulates GABAergic transmission and enhances inhibitory postsynaptic currents in substantia nigra dopaminergic neurons. ARMET/MANF Protein, Human (His) is the recombinant human-derived ARMET/MANF protein, expressed by E. coli , with N-6*His labeled tag. The total length of ARMET/MANF Protein, Human (His) is 158 a.a., with molecular weight of ~20 kDa.
  • HY-P7605
    ARMET/MANF Protein, Human (158a.a, HEK293, His)

    rHuARMET/MANF, His; Mesencephalic astrocyte-derived neurotrophic factor; ARMET

    		Human HEK293
    ARMET/MANF Protein, Human (158a.a, HEK293, His) expresses in HEK293 cells with a His tag. Armet/MANF, localized in the ER and Golgi, is a secreted protein and acts as a gene up-regulated by various forms of ER stress.
  • HY-P77296
    ARMET/MANF Protein, Mouse (HEK293, His)

    Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP

    		Mouse HEK293
    ARMET/MANF proteins regulate the survival of dopaminergic neurons in the ventral midbrain and modulate GABAergic transmission to dopaminergic neurons in the substantia nigra. It enhances GABA inhibitory currents and inhibits cell proliferation while preventing ER stress-induced cell death. ARMET/MANF Protein, Mouse (HEK293, His) is the recombinant mouse-derived ARMET/MANF protein, expressed by HEK293 , with C-His labeled tag. The total length of ARMET/MANF Protein, Mouse (HEK293, His) is 179 a.a., with molecular weight of ~21 kDa.
  • HY-P76731
    ARMET/MANF Protein, Human (HEK293, Fc)

    Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP

    		Human HEK293
    ARMET/MANF Protein is an evolutionary conserved endoplasmic reticulum stress- (ERS-) related protein. ARMET/MANF has a protective effect on central nervous system diseases and plays an important role in several metabolic diseases. It is mainly localized to the luminal endoplasmic reticulum (ER) as an ER chaperone protein, mainly interacting with BiP and Reticulon 1-C. Meanwhile, MANF can prevent ER stress-mediated cell death in neurons and other tissues. ARMET/MANF Protein, Human (HEK293, Fc) is the recombinant human-derived ARMET/MANF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ARMET/MANF Protein, Human (HEK293, Fc) is 182 a.a., with molecular weight of ~44.9 KDa.
Cat. No. Product Name Effect Purity