2. Recombinant Proteins
  3. Ubiquitin Related Proteins
  4. Deubiquitinase
  5. Ubiquitin-Specific Protease
  6. Ubiquitin-Specific Protease 5

Ubiquitin-Specific Protease 5

Recombinant Protein Expression Service

Ubiquitin-Specific Protease 5

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Cat. No. Product Name / Synonyms Species Source
  • HY-P74479
    USP5 Protein, Human (sf9, His)

    Ubiquitin carboxyl-terminal hydrolase 5; Isopeptidase T; USP5; ISOT

    		Human Sf9 insect cells
    USP5 protein selectively cleaves branched multiubiquitin polymers, favoring 'Lys-48'-linked polyubiquitin disassembly. It exhibits lower affinity for linear and 'Lys-63'-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of USP5 Protein, Human (sf9, His) is 835 a.a., with molecular weight of ~100 kDa.
Cat. No. Product Name Effect Purity