1. Recombinant Proteins
  2. TGF beta 3 Protein, Human/Mouse/Rat (HEK293)

TGF beta 3 Protein, Human/Mouse/Rat (HEK293)

Cat. No.: HY-P7120
Handling Instructions

TGF beta 3 Protein, Human/Mouse/Rat (HEK293) is a multifunctional cytokine which participated in cell differentiation, embryogenesis and development.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $190 In-stock
Estimated Time of Arrival: December 31
50 μg $790 In-stock
Estimated Time of Arrival: December 31
100 μg $1050 Get quote
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rHuTGF-β3; TGFB3; LAP
Species

Human

Source

HEK 293

Accession

P10600 (A301-S412)

Gene ID

7043

Molecular Weight

Approximately 12.7 kDa

AA Sequence

ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS

Biological Activity
The ED50 is <0.2 ng/mL as measured in a cell proliferation assay using mouse HT-2 cells.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 4 mM HCl.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Transforming growth factor-β (TGF-β) is a glycoprotein that acts as a cytokine. This multifunctional cytokine has a pivotal role in the regulation of many cellular activities, such as proliferation, differentiation, and other functions, and also plays a role in immunity, cancer, heart disease, diabetes, Marfan syndrome, Loeys–Dietz syndrome, Parkinson's disease, and AIDS. Three TGF-β isoforms have been found in mammals: TGF-β1, 2, and 3, which are structurally and functionally similar. Transforming Growth Factor β3 expression increases in fetal wound healing and reduces fibronectin and collagen I and III deposition, and also improves the architecture of the neodermis which is a combination of blood vessels and connective tissue during wound healing[1]. Transforming Growth Factor β3 has been found to have an important role in normal developmental biology including systems such as the heart, lung and breast and to display isoform-specific biology at both the in vivo and in vitro level[2].

Documentation
References
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
TGF beta 3 Protein, Human/Mouse/Rat (HEK293)
Cat. No.:
HY-P7120
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