Neomycin

68 Cited Publications
고객리뷰

Based on 68 publication(s) in Google Scholar

Neomycin, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin is a known phospholipase C (PLC) inhibitor. Neomycin potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin inhibits IP3-mediated Ca2+ release, MgATP-dependent Ca2+ uptake, and electrical excitation-evoked skeletal muscle Ca2+ transients. Neomycin depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin can be used for the research of cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Biological Activity
  • Chemical Information
  • 순도&문서
  • References
  • Help & FAQs

Publications Citing Use of MedChemExpress (MCE) Neomycin

More
Customer Validation & Images
In Vivo Efficacy StudyPK/PD AnalysisOthersBio/Physico-chemical Assay
  • In Vivo Efficacy Study
  • Others
  • PK/PD Analysis
  • Bio/Physico-chemical Assay

All Phospholipase Isoforms

More
100 mg

견적 받기 해외재고보유

Please select quantity
Amount: USD 0.00