2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. NK Cell CD Proteins Killer-Cell Immunoglobulin-like Receptors
  5. CD158z/KIR3DL3
  6. KIR3DL3/CD158z Protein, Human (HEK293, His-Avi)

KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

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Descripciòn

KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Background

KIR3DL3, present on natural killer cells, acts as a receptor that potentially inhibits NK cell activity, thereby contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating the functions of NK cells and maintaining immune homeostasis.
Species

Human
Source

HEK293
Tag

C-Avi;C-8*His
Accession

Q8N743 (E26-L322)
Gene ID
Molecular Construction
N-term
CD158z (E26-L322)
Accession # Q8N743
8*His-Avi
C-term
Protein Length

Extracellular Domain
Synonyms
CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3
Predicted Molecular Mass
35.3 kDa
Peso molecular

Approximately 48-52 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Pureza

≥ 95%, as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentación
Instrucciones de manejo (2659 KB)

KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KIR3DL3/CD158z Protein, Human (HEK293, His-Avi)
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