1. Cytoskeleton
    Anti-infection
  2. Arp2/3 Complex
    Bacterial
    Antibiotic
  3. Cytochalasin D

Cytochalasin D (Synonyms: Zygosporin A; NSC 209835)

Cat. No.: HY-N6682 Purity: >99.0%
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Cytochalasin D (Zygosporin A; NSC 209835) is a potent and cell-permeable inhibitor of actin polymerization derived from fungus, inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D (Zygosporin A; NSC 209835) also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells.Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment.

For research use only. We do not sell to patients.

Cytochalasin D Chemical Structure

Cytochalasin D Chemical Structure

CAS No. : 22144-77-0

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Estimated Time of Arrival: December 31
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Based on 2 publication(s) in Google Scholar

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Description

Cytochalasin D (Zygosporin A; NSC 209835) is a potent and cell-permeable inhibitor of actin polymerization derived from fungus, inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D (Zygosporin A; NSC 209835) also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells[1][2][3].Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment[4].

IC50 & Target

G-actin[1]

Clinical Trial
Molecular Weight

507.62

Formula

C₃₀H₃₇NO₆

CAS No.

22144-77-0

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Keywords:

Cytochalasin DZygosporin ANSC 209835NSC209835NSC-209835Arp2/3 ComplexBacterialAntibioticActin-related protein 2/3 complex Inhibitorinhibitorinhibit

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Cytochalasin D
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