FCAMR/CD351 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
FCAMR/CD351, functioning as a receptor, exhibits high-affinity binding to the Fc fragment of IgA and IgM. It plays a role in the immune response by mediating the endocytosis of IgA and IgM during the immune response to microbes. FCAMR/CD351 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FCAMR/CD351 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
FCAMR/CD351, functioning as a receptor, exhibits high-affinity binding to the Fc fragment of IgA and IgM. It plays a role in the immune response by mediating the endocytosis of IgA and IgM during the immune response to microbes. FCAMR/CD351 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FCAMR/CD351 protein, expressed by HEK293 , with C-His labeled tag.
Background
FCAMR/CD351 protein serves as a crucial receptor for the Fc fragment of immunoglobulin A (IgA) and immunoglobulin M (IgM), exhibiting a high-affinity binding capacity for these immunoglobulins and facilitating their endocytosis. The protein is implicated in immune responses to microbes mediated by IgA and IgM, playing a pivotal role in the recognition and internalization of these antibodies.
Verified Bioactivity
Immobilized FCAMR/CD351 at 2 μg/mL (100 μL/well) can bind Mouse IgM Protein. The ED50 for this effect is 0.05460 μg/mL.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-His
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Accession
Q2TB54-2/NP_001164103.1 (M92-R511)
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Molecular Construction
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N-term
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FCAMR (M92-R511)
Accession # Q2TB54-2/NP_001164103.1 -
His
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C-term
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Protein Length
Partial
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Synonyms
FCAMR; CD351; Fc Alpha And Mu Receptor; Fc Receptor, IgA, IgM, High Affinity; Fc Alpha/Mu Receptor; Fc Fragment Of IgA And IgM Receptor; High Affinity Immunoglobulin Alpha And Immunoglobulin Mu Fc Receptor; Receptor For Fc Fragment Of IgA And IgM; Fcalpha
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AA Sequence
MTPPHRRSHSRWLQAGSPQFRTHLYNVEAHTAPTPLCCWKNSLSGTNALRGPRLVTGNTGGAVTIHCHYAPSSVNRHQRKYWCRLGSPLWICHTVVSTNQYTHPDYRGRAALTDIPQSGLFVVRLLRLSLGDVGLYRCGIGDRNDMLFFSVNLTVSAGPSNTTYAAAPASGEPTTASPGAASSAGNGWTSGITQILEGSGSEWDRTVPTTGTSKTTSSANGRQTLRTARTMVPGTGSREEGSIRAAVPTPEGPSPKSRSMSSTTQGVWLWSTRNSVTPSVTTSEGRRQGTTPETDGPRDETDVRVSPEAPRKTTGTTRPSALISEHVTWETLQDKTEVSKQQMLHSLEELSPAPSAQTLNATCLEVASEEGRSIDGSLENTTEESSPPTPSQLSVAGPVWVSVKGPSMKSALMEGESHTR
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Predicted Molecular Mass
46.4 kDa
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (237 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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