1. Recombinant Proteins
  2. Fc Receptors
  3. Fc alpha/mu Receptor
  4. FCAMR/CD351 Protein, Mouse (HEK293, His)

FCAMR/CD351 Protein, Mouse (HEK293, His)

Cat. No.: HY-P77363
COA Handling Instructions

FCAMR/CD351, functioning as a receptor, exhibits high-affinity binding to the Fc fragment of IgA and IgM. It plays a role in the immune response by mediating the endocytosis of IgA and IgM during the immune response to microbes. FCAMR/CD351 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FCAMR/CD351 protein, expressed by HEK293 , with C-His labeled tag. The total length of FCAMR/CD351 Protein, Mouse (HEK293, His) is 420 a.a., with molecular weight of ~46.4 KDa.

For research use only. We do not sell to patients.

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Description

FCAMR/CD351, functioning as a receptor, exhibits high-affinity binding to the Fc fragment of IgA and IgM. It plays a role in the immune response by mediating the endocytosis of IgA and IgM during the immune response to microbes. FCAMR/CD351 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FCAMR/CD351 protein, expressed by HEK293 , with C-His labeled tag. The total length of FCAMR/CD351 Protein, Mouse (HEK293, His) is 420 a.a., with molecular weight of ~46.4 KDa.

Background

FCAMR/CD351 protein serves as a crucial receptor for the Fc fragment of immunoglobulin A (IgA) and immunoglobulin M (IgM), exhibiting a high-affinity binding capacity for these immunoglobulins and facilitating their endocytosis. The protein is implicated in immune responses to microbes mediated by IgA and IgM, playing a pivotal role in the recognition and internalization of these antibodies.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q2TB54-2/NP_001164103.1 (M92-R511)

Gene ID

64435  [NCBI]

Molecular Construction
N-term
FCAMR (M92-R511)
Accession # Q2TB54-2/NP_001164103.1
His
C-term
Synonyms
High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor; Fc alpha/mu receptor; uR
Molecular Weight

Approximately 46.4 kDa.

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Solution

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

FCAMR/CD351 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FCAMR/CD351 Protein, Mouse (HEK293, His)
Cat. No.:
HY-P77363
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