2. Cell Cycle/DNA Damage Apoptosis
  3. DNA/RNA Synthesis Apoptosis
  4. 2,4-D sodium salt

2,4-D sodium salt  (Synonyms: Sodium 2,4-dichlorophenoxyacetate; 2,4-Dichlorophenoxyacetic acid sodium salt)

Cat. No.: HY-18572A
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2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D sodium salt can induce < b>apoptosis. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development.

For research use only. We do not sell to patients.

2,4-D sodium salt Chemical Structure

2,4-D sodium salt Chemical Structure

CAS No. : 2702-72-9

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Based on 1 publication(s) in Google Scholar

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2,4-D sodium salt Related Antibodies

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Description

2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D sodium salt can induce < b>apoptosis. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].

In Vitro

2, 4-D sodium salt (25-200 μM, 72 h) inhibits the cell viability of A549 and WI38 with IC50 values of 126 ± 2.25µM and 115 ± 4.39µM, respectively. By influencing cell cycle, apoptosis was induced[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2,4-D sodium salt Related Antibodies

Cell Viability Assay[2]

Cell Line: A549, W138
Concentration: 25, 50, 75, 100, 150, 200 μM
Incubation Time: 72 h
Result: Inhibited cell viability in a dose-dependent manner.

Cell Cytotoxicity Assay[2]

Cell Line: A549
Concentration: 50, 100, 150 μM
Incubation Time: 72 h
Result: The G0/G1 population decreased to about 57%, 43% and 31%, respectively.

Apoptosis Analysis[2]

Cell Line: A549, W138
Concentration: 100, 150 μM
Incubation Time: 72 h
Result: The early apoptotic population increased to 44% in A549 cells and 57% in WI38 cells, and the late apoptotic population increased to 18% in A549 cells and 10% in WI38 cells.

Western Blot Analysis[2]

Cell Line: A549, W138
Concentration: 100, 150 μM
Incubation Time: 72 h
Result: Up-regulated p53 and Bax proteins, down-regulated Bcl-2 and pro caspase 3.
In Vivo

2,4-D sodium salt (100 or 200 mg/kg, gavage for 30 days) has toxic effects on the reproductive system of male rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult Wistar male rats[3]
Dosage: 100 or 200 mg/kg
Administration: i.g.
Result: Decreased the testis , seminal vesicles and prostate relative weight.
Decreased the number of spermatozoa and sperm motility.
Increased the level of FSH and LH.
Molecular Weight

243.02

Formula

C8H5Cl2NaO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])COC1=CC=C(Cl)C=C1Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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2,4-D sodium salt Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,4-D2702-72-9Sodium 2,4-dichlorophenoxyacetate2,4-Dichlorophenoxyacetic acidDNA/RNA SynthesisApoptosisA549W138HerbicideFSH， LHInhibitorinhibitorinhibit

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