1. Peptides
  2. His-[D-2-ME-Trp]-Ala

His-[D-2-ME-Trp]-Ala is a fragment of the growth hormone hexarelin.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

His-[D-2-ME-Trp]-Ala Chemical Structure

His-[D-2-ME-Trp]-Ala Chemical Structure

Size Price Stock Quantity
1 mg USD 90 In-stock
5 mg USD 220 In-stock
10 mg USD 350 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

His-[D-2-ME-Trp]-Ala is a fragment of the growth hormone hexarelin.

Molecular Weight

426.47

Formula

C21H26N6O4

Appearance

Solid

Color

White to off-white

Sequence

His-{d-2-Me-Trp}-Ala

Sequence Shortening

H-{d-2-Me-Trp}-A

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (117.24 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3448 mL 11.7242 mL 23.4483 mL
5 mM 0.4690 mL 2.3448 mL 4.6897 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (234.48 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.3448 mL 11.7242 mL 23.4483 mL 58.6208 mL
5 mM 0.4690 mL 2.3448 mL 4.6897 mL 11.7242 mL
10 mM 0.2345 mL 1.1724 mL 2.3448 mL 5.8621 mL
15 mM 0.1563 mL 0.7816 mL 1.5632 mL 3.9081 mL
20 mM 0.1172 mL 0.5862 mL 1.1724 mL 2.9310 mL
25 mM 0.0938 mL 0.4690 mL 0.9379 mL 2.3448 mL
30 mM 0.0782 mL 0.3908 mL 0.7816 mL 1.9540 mL
40 mM 0.0586 mL 0.2931 mL 0.5862 mL 1.4655 mL
50 mM 0.0469 mL 0.2345 mL 0.4690 mL 1.1724 mL
60 mM 0.0391 mL 0.1954 mL 0.3908 mL 0.9770 mL
80 mM 0.0293 mL 0.1466 mL 0.2931 mL 0.7328 mL
100 mM 0.0234 mL 0.1172 mL 0.2345 mL 0.5862 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
His-[D-2-ME-Trp]-Ala
Cat. No.:
HY-P1460
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