2. Natural Products
  3. Terpenoids
  4. Sesquiterpenes

Sesquiterpenes

Sesquiterpenes (366):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0176
    Dihydroartemisinin 71939-50-9 99.03%
    Dihydroartemisinin is a potent anti-malaria agent.
    Dihydroartemisinin
  • HY-N0193
    Artesunate 88495-63-0 98.09%
    Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
    Artesunate
  • HY-N0141
    Parthenolide 20554-84-1 99.94%
    Parthenolide is a sesquiterpene lactone found in the medicinal herb Feverfew. Parthenolide exhibits anti-inflammatory activity by inhibiting NF-κB activation; also inhibits HDAC1 protein without affecting other class I/II HDACs.
    Parthenolide
  • HY-B0094
    Artemisinin 63968-64-9 98.40%
    Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
    Artemisinin
  • HY-N1415
    β-Caryophyllene 87-44-5 99.55%
    β-Caryophyllene is a CB2 receptor agonist.
    β-Caryophyllene
  • HY-N0176A
    α-Dihydroartemisinin 81496-81-3
    α-Dihydroartemisinin is a natural product that can be found in artemisinin. α-Dihydroartemisinin also shows antimalarial activity.
    α-Dihydroartemisinin
  • HY-N3512
    Wilfornine A 345954-00-9
    Wilfornine A is a natural product that can be isolated from Schisandra sphenanthera. Wilfornine A has anti-tumor effect.
    Wilfornine A
  • HY-N3879
    Eudesm-4(14)-ene-3α,11-diol 113773-90-3
    Eudesm-4(14)-ene-3α,11-diol (compound 2) is a sesquiterpenoid. Eudesm-4(14)-ene-3α,11-diol can be isolated from Neocallitropsis Pancheri Florin.
    Eudesm-4(14)-ene-3α,11-diol
  • HY-100560
    Abscisic acid 21293-29-8 99.72%
    Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump (H+-ATPase) and leads to the plasma membrane depolarization in a Ca2+-dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome.
    Abscisic acid
  • HY-N0038
    Alantolactone 546-43-0 99.94%
    Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer.
    Alantolactone
  • HY-107324
    β-Elemene 515-13-9 99.58%
    β-Elemene ((-)-β-Elemene; Levo-β-elemene) is isolated from natural plant Curcuma aromatica with an antitumor activity. β-Elemene can induce cell apoptosis.
    β-Elemene
  • HY-N0201
    Atractylenolide I 73069-13-3 99.87%
    Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.
    Atractylenolide I
  • HY-N0036
    Costunolide 553-21-9 99.97%
    Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells.
    Costunolide
  • HY-N0104
    Curcumol 4871-97-0 99.50%
    Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers.
    Curcumol
  • HY-N0076
    Bilobalide 33570-04-6 ≥98.0%
    Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 µM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons.
    Bilobalide
  • HY-17387
    (-)-Huperzine A 102518-79-6 99.74%
    (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease.
    (-)-Huperzine A
  • HY-N0402
    Artemether 71963-77-4 98.42%
    Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
    Artemether
  • HY-N0710
    alpha-Cyperone 473-08-5 99.80%
    alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
    alpha-Cyperone
  • HY-16059
    Arglabin 84692-91-1 99.87%
    Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities. The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene.
    Arglabin
  • HY-N0203
    Atractylenolide III 73030-71-4 99.94%
    Atractylenolide III (ICodonolactone) is the main component of Atractylodes rhizome and has the activity of inducing apoptosis in lung cancer cells. Atractylenolide III is an orally active gastroprotective agent.
    Atractylenolide III