2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. c-Met/HGFR
  5. c-Met/HGFR Activator

c-Met/HGFR Activator

c-Met/HGFR Activators (2):

Cat. No. Product Name Effect Purity
  • HY-16969
    Dihexa
    		Activator 99.21%
    Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease.
  • HY-137455
    Terevalefim
    		Activator 99.89%
    Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor.