2. Apoptosis
  3. Apoptosis
  4. [Ag(2,2′-bipy)(dppe)][CF3SO3]

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) can induce cell paraptosis, and can be used for stusy of resistant ovarian cancer.

For research use only. We do not sell to patients.

[Ag(2,2′-bipy)(dppe)][CF3SO3] Chemical Structure

[Ag(2,2′-bipy)(dppe)][CF3SO3] Chemical Structure

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[Ag(2,2′-bipy)(dppe)][CF3SO3] Related Antibodies

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Description

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) can induce cell paraptosis, and can be used for stusy of resistant ovarian cancer[1].

In Vitro

[Ag(2,2′-bipy)(dppe)][CF3SO3] (compound 4) (0-10 μM,72 h) inhibits cell growth of SK-OV-3, SK-OV-3/CBP, HCT116 WT and HCT116 WT/OxR with the IC50 values of 6.8 μM, 5.48 μM, 0.70 μM and 0.65 μM, respectively[1].
[Ag(2,2′-bipy)(dppe)][CF3SO3] (10 μM, 24 h) induces cell apoptosis of SK-OV-3 and MES-OV cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[Ag(2,2′-bipy)(dppe)][CF3SO3] Related Antibodies

Cell Viability Assay[1]

Cell Line: SK-OV-3、SK-OV-3/CBP、HCT116 WT and HCT116 WT/OxR cells.
Concentration: 0-10 μM
Incubation Time: 72 h
Result: Inhibited cell growth with the IC50 values of 6.8 μM, 5.48 μM, 0.70 μM and 0.65 μM of SK-OV-3, SK-OV-3/CBP, HCT116 WT and HCT116 WT/OxR , respectively.

Apoptosis Analysis[1]

Cell Line: SK-OV-3 and MES-OV cells
Concentration: 10 μM
Incubation Time: 24 h
Result: Induced cell apoptosis.
Molecular Weight

811.54

Formula

C37H32AgF3N2O3P2S-
SMILES

FC(F)(S(=O)([O-])=O)F.C1([P]2(CC[P](C3=CC=CC=C3)([Ag]24[N]5=CC=CC=C5C6=CC=CC=[N]64)C7=CC=CC=C7)C8=CC=CC=C8)=CC=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[Ag(2,2′-bipy)(dppe)][CF3SO3] Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ag(2,2′-bipy)(dppe)][CF3SO3]ApoptosisHCT116SK-OV-3MES-OVcell paraptosisInhibitorinhibitorinhibit

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[Ag(2,2′-bipy)(dppe)][CF3SO3]
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