1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 154

Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent. Antibacterial agent 154 inhibits Gram-positive and Gram-negative bacteria. Antibacterial agent 154 demonstrated in vivo efficacy in a mouse model of staphylococcal sepsis.

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Antibacterial agent 154 Chemical Structure

Antibacterial agent 154 Chemical Structure

CAS No. : 2163048-45-9

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Description

Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent. Antibacterial agent 154 inhibits Gram-positive and Gram-negative bacteria. Antibacterial agent 154 demonstrated in vivo efficacy in a mouse model of staphylococcal sepsis[1].

In Vitro

Antibacterial agent 154 (compound 7) inhibits Gram-positive bacteria M. luteus, B. subtilis, S. aureus, and S. epidermidis. The MICs are 4 μg/mL, 2 μg/mL, 2 μg/mL, and 2 μg/ mL; the MICs for inhibiting Gram-negative bacteria P. aerugenosa, E. coli, and S. typhimurium are 2 μg/mL and 2 μg/mL respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

518.97

Formula

C25H28ClFN4O5

CAS No.
SMILES

OC1=C(C)N=CC(CN2CCN(C3=C(F)C=C4C(N(C5CC5)C=C(C(O)=O)C4=O)=C3)CC2)=C1CO.Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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Antibacterial agent 154 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Antibacterial agent 154
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HY-155250
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