1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. DDB1 Antibody (YA785)

DDB1 Antibody (YA785)

Cat. No.: HY-P80641
User Guide for Antibodies

DDB1 Antibody (YA785) is a non-conjugated and Mouse origined monoclonal antibody about 127 kDa, targeting to DDB1 (2D6). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

DDB1 Antibody (YA785) is a non-conjugated and Mouse origined monoclonal antibody about 127 kDa, targeting to DDB1 (2D6). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

Background

DDB1 (2D6): The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012]

Tag

Free

Gene ID

1642

Synonyms
XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
Molecular Weight

Predicted band size: 127 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Mouse, Rat, Monkey

SwissProt ID

Q16531

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG2b

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human DDB1.The exact sequence is proprietary to MCE.

Documentation

DDB1 Antibody (YA785) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
DDB1 Antibody (YA785)
Cat. No.:
HY-P80641
Quantity:
MCE Japan Authorized Agent: