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  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. Thioredoxin Reductase 2 Antibody (YA661)

Thioredoxin Reductase 2 Antibody (YA661)

Cat. No.: HY-P80913
User Guide for Antibodies

Thioredoxin Reductase 2 Antibody (YA661) is a non-conjugated and Mouse origined monoclonal antibody about 57 kDa, targeting to Thioredoxin Reductase 2 (3F2). It can be used for WB assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

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10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Description

Thioredoxin Reductase 2 Antibody (YA661) is a non-conjugated and Mouse origined monoclonal antibody about 57 kDa, targeting to Thioredoxin Reductase 2 (3F2). It can be used for WB assays with tag free, in the background of Human.

Background

Thioredoxin Reductase 2 (3F2): The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene. [provided by RefSeq, Jun 2017]

Tag

Free

Gene ID

10587

Synonyms
mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.
Molecular Weight

Predicted band size: 57 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cell Biology

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

SwissProt ID

Q9NNW7

Dilution Ratio

WB: 1:500-1:1,000

Application

WB

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human TXNRD2.The exact sequence is proprietary to MCE.

Documentation

Thioredoxin Reductase 2 Antibody (YA661) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thioredoxin Reductase 2 Antibody (YA661)
Cat. No.:
HY-P80913
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