2. Anti-infection
  3. Fungal
  4. Antifungal agent 30

Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51.

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Antifungal agent 30 Chemical Structure

Antifungal agent 30 Chemical Structure

CAS No. : 2422019-91-6

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Description

Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].

Molecular Weight

446.18

Formula

C18H14Cl2F2N2Se
CAS No.
SMILES

FC1=CC(F)=C(C=C1)C([Se]CC2=C(C=C(C=C2)Cl)Cl)CN3C=CN=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antifungal agent 30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 302422019-91-6Antifungal agent30Antifungal agent-30FungalMiconazoleAntifungalSeleniumBioisosterismCYP51Candida albicansAspergillus fumigatusInhibitorinhibitorinhibit

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