2. Anti-infection Protein Tyrosine Kinase/RTK
  3. Parasite Ephrin Receptor
  4. Antimalarial agent 37

Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7.

For research use only. We do not sell to patients.

Antimalarial agent 37 Chemical Structure

Antimalarial agent 37 Chemical Structure

CAS No. : 2982633-16-7

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Antimalarial agent 37 Related Antibodies

Top Publications Citing Use of Products

View All Parasite Isoform Specific Products:

View All Isoforms

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7[1].

In Vitro

Antimalarial agent 37 (0-50 nM, 72 h) exhibits antiplasmodial activities, with EC50 values of 31 nM and 35 nM for strains Dd2 and 3D7, respectively[1].
Antimalarial agent 37 exhibits microsomal stability in mouse liver microsome with half-time of 41.4 min and clearance of 17 μL/min/mg[1].
Antimalarial agent 37 (0-5000 nM, 48 h) reveals cytotoxicity in cells HepG2 and MCF 7, with EC50 values of 2850 and 3540 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antimalarial agent 37 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: P. falciparum Dd2 and P. falciparum 3D7 strains
Concentration: 0-50 nM
Incubation Time: 72 h
Result: Exhibited antiplasmodial activities with EC50 values of 31 nM and 35 nM for strains Dd2 and 3D7.

Cell Viability Assay[1]

Cell Line: HepG2, MCF7
Concentration: 0-5000 nM
Incubation Time: 48 h
Result: Revealed cytotoxicity in HepG2 and MCF7, with EC50 values of 2850 nM and 3540 nM as well as selectivity index of 92 and 114, respectively
Molecular Weight

661.66

Formula

C32H29F6N5O2S
CAS No.
SMILES

CCN1CCN(CC1)CC2=CC=C(C=C2C(F)(F)F)NC(C3=CC(NC(C4=CC(C5=CC=CS5)=CN=C4)=O)=CC(C(F)(F)F)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Antimalarial agent 37 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 372982633-16-7Antimalarial agent37Antimalarial agent-37ParasiteEphrin ReceptorantimalarialP. falciparumHepG2MCF7Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Antimalarial agent 37
Cat. No.:
HY-161171
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.