2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Antitumor agent-63

Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition.

For research use only. We do not sell to patients.

Antitumor agent-63 Chemical Structure

Antitumor agent-63 Chemical Structure

CAS No. : 1627600-90-1

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Antitumor agent-63 Related Antibodies

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Description

Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].

IC50 & Target

Top1

 

In Vitro

Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-63 Related Antibodies
Molecular Weight

846.79

Formula

C38H46N4O18
CAS No.
SMILES

O[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)OC(N)=O)[C@H]1O[C@@H]([C@H]([C@@H]([C@@H](O2)CO)O)O)[C@H]2OCCOCCNC(O[C@]3(C4=C(COC3=O)C(N5C(C6=NC7=CC=CC=C7C=C6C5)=C4)=O)CC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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Antitumor agent-63 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-631627600-90-1Antitumor agent63Antitumor agent 63TopoisomeraseHepG2HCT116SW1990HEK-293antitumorInhibitorinhibitorinhibit

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