AR-13324 analog mesylate

Cat. No.: HY-19346 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor.

For research use only. We do not sell to patients.

AR-13324 analog mesylate Chemical Structure

CAS No. : 2095432-73-6

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 584	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 584	In-stock	Estimated Time of Arrival: December 31
Liquid
5 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 600	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of AR-13324 analog mesylate:

Netarsudil dimesylate In-stock
Netarsudil hydrochloride In-stock

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All ROCK Isoform Specific Products:

View All Isoforms

Biological Activity
Purity & Documentation
References
Customer Review

Description

AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor^[1].

Molecular Weight

631.72

Formula

C₂₉H₃₃N₃O₉S₂

CAS No.

2095432-73-6

Appearance

Liquid

Color

Light brown to brown

SMILES

CS(=O)(O)=O.CS(=O)(O)=O.O=C(OC1=CC=C([C@@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 28 mg/mL (44.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5830 mL	7.9149 mL	15.8298 mL
5 mM	0.3166 mL	1.5830 mL	3.1660 mL
10 mM	0.1583 mL	0.7915 mL	1.5830 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (280 KB) SDS (0 KB)

COA (262 KB) HNMR (156 KB)

Handling Instructions (2659 KB)

References

[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. [Content Brief]

[2]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. [Content Brief]

[3]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5830 mL	7.9149 mL	15.8298 mL	39.5745 mL
	5 mM	0.3166 mL	1.5830 mL	3.1660 mL	7.9149 mL
	10 mM	0.1583 mL	0.7915 mL	1.5830 mL	3.9574 mL
	15 mM	0.1055 mL	0.5277 mL	1.0553 mL	2.6383 mL
	20 mM	0.0791 mL	0.3957 mL	0.7915 mL	1.9787 mL
	25 mM	0.0633 mL	0.3166 mL	0.6332 mL	1.5830 mL
	30 mM	0.0528 mL	0.2638 mL	0.5277 mL	1.3191 mL
	40 mM	0.0396 mL	0.1979 mL	0.3957 mL	0.9894 mL