TBC1 domain family member 10B

Definition:

Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, and RAB35. Does not act on RAB2A and RAB6A.

References:

[1]. Takashi Itoh, et al. Identification of EPI64 as a GTPase-activating protein specific for Rab27A. J Biol Chem. 2006 Oct 20;281(42):31823-31. [Content Brief]

[2]. Koutaro Ishibashi, et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Genes Cells. 2009 Jan;14(1):41-52. [Content Brief]

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