Tetrahydrofolate (THF)

Definition:

Tetrahydrofolate (THF) is a folic acid derivative, exhibits a high antioxidant activity in oxidative stress. Tetrahydrofolate (THF) mitigates the inhibitory effect of oxidative stress on neural stem cell (NSC) proliferation via PTEN/Akt/mTOR signaling pathway.

References:

[1]. Zhang X, et al. Tetrahydrofolate Alleviates the Inhibitory Effect of Oxidative Stress on Neural Stem Cell Proliferation through PTEN/Akt/mTOR Pathway. Oxid Med Cell Longev. 2022 Feb 27;2022:9021474. [Content Brief]

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