The tricarboxylic acid (TCA) cycle

Definition:

The tricarboxylic acid (TCA) cycle is the final common oxidative pathway for carbohydrates, fats and amino acids. TCA cycle also is a central route for oxidative phosphorylation in cells, and fulfills their bioenergetic, biosynthetic, and redox balance requirements.

References:

[1]. Nicole M Anderson, et al. The emerging role and targetability of the TCA cycle in cancer metabolism. Protein Cell. 2018 Feb;9(2):216-237. [Content Brief]

[2]. Muhammad Akram, et al. Citric acid cycle and role of its intermediates in metabolism. Cell Biochem Biophys. 2014 Apr;68(3):475-8. [Content Brief]

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