Trafficking protein particle complex subunit 8

Definition:

Plays a role in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Maintains together with TBC1D14 the cycling pool of ATG9 required for initiation of autophagy.

References:

[1]. Christopher A Lamb, et al. TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic. EMBO J. 2016 Feb 1;35(3):281-301. [Content Brief]

[2]. P James Scrivens, et al. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Mol Biol Cell. 2011 Jun 15;22(12):2083-93. [Content Brief]

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