Transcriptional repressor scratch 1

Definition:

Transcriptional repressor that binds E-box motif CAGGTG. Can modulate the action of basic helix-loop-helix (bHLH) transcription factors, critical for neuronal differentiation.

References:

[1]. E K Nakakura, et al. Mammalian Scratch: a neural-specific Snail family transcriptional repressor. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4010-5. [Content Brief]

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