Transmembrane protein 165

Definition:

May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation.

References:

[1]. François Foulquier, et al. TMEM165 deficiency causes a congenital disorder of glycosylation. Am J Hum Genet. 2012 Jul 13;91(1):15-26. [Content Brief]

[2]. Didier Demaegd, et al. Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6859-64. [Content Brief]

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