Transmembrane protein 223

Definition:

Mitochondrial ribosome-associated protein involved in the first steps of cytochrome c oxidase complex (complex IV) biogenesis. Stimulates the translation of MT-CO1 mRNA and is a constituent of early MT-CO1 assembly intermediates.

References:

[1]. Sven Dennerlein, et al. Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors. Elife. 2021 Dec 31;10:e68213. [Content Brief]

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