Transmembrane protein 74

Definition:

Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.

References:

[1]. Chuanfei Yu, et al. TMEM74, a lysosome and autophagosome protein, regulates autophagy. Biochem Biophys Res Commun. 2008 May 2;369(2):622-9. [Content Brief]

[2]. Pengfei He, et al. High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene. Autophagy. 2009 Jan;5(1):52-60. [Content Brief]

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