Tyrosine-protein phosphatase non-receptor type 5

Definition:

May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.

References:

[1]. Saibal Mukherjee, et al. Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP. Biochem J. 2011 Nov 15;440(1):115-25. [Content Brief]

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