2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Boc-Val-Ala-PAB-PNP

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Boc-Val-Ala-PAB-PNP Chemical Structure

Boc-Val-Ala-PAB-PNP Chemical Structure

CAS No. : 1884578-00-0

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500 mg USD 560 In-stock
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Based on 1 publication(s) in Google Scholar

Boc-Val-Ala-PAB-PNP Related Antibodies

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Description

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Protease Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-Val-Ala-PAB-PNP Related Antibodies
Molecular Weight

558.58

Formula

C27H34N4O9
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

CC([C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(NC1=CC=C(C=C1)COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)C)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Boc-Val-Ala-PAB-PNP Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Val-Ala-PAB-PNP1884578-00-0ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
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