2. Natural Products
  3. Disease Research Fields Plants Food Research Phenols
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  5. Ulmus davidiana var. japonica (Rehd.)Nakai
  6. Catechin 7-O-β-D-glucopyranoside

Catechin 7-O-β-D-glucopyranoside 

Cat. No.: HY-N10587 Purity: 99.48%
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Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research.

For research use only. We do not sell to patients.

Catechin 7-O-β-D-glucopyranoside Chemical Structure

Catechin 7-O-β-D-glucopyranoside Chemical Structure

CAS No. : 65597-47-9

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Catechin 7-O-β-D-glucopyranoside Related Antibodies

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Description

Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].

In Vitro

Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Catechin 7-O-β-D-glucopyranoside Related Antibodies

Western Blot Analysis[3]

Cell Line: RINm5F rat pancreatic β-cells
Concentration: 10 μg/mL
Incubation Time: 24 hours
Result: Increased the MnSOD level attenuated by Streptozotocin treatment.
Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
In Vivo

Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN[1].
Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice injected with LPS/D-GalN[1]
Dosage: 10 mg/kg
Administration: Intraperitoneal injection; 10 mg/kg; once
Result: Showed 80% LPS/DGalN-induced lethality in mice.
Animal Model: Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis [2]
Dosage: 10 mg/kg
Administration: Oral administration; 10 mg/kg; once daily; 7 days
Result: Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats.
Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
Molecular Weight

452.41

Formula

C21H24O11
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C2C(O[C@H](C3=CC(O)=C(C=C3)O)[C@H](C2)O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Catechin 7-O-β-D-glucopyranoside65597-47-9Othersantioxidant activityanti-inflammatory activitymitochondrial dysfunctionRINm5F rat pancreatic β-cellInhibitorinhibitorinhibit

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