REG3G - regenerating family member 3 gamma Gene

Homo sapiens

Also known as PAP1B; PAPIB; PAP IB; PAP-1B; UNQ429; LPPM429; REG III; REG-III

Gene ID: 130120 | Gene type: protein coding

About REG3G

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:79,025,702-79,028,501 (from NCBI)

This gene has 5 transcripts (splice variants), 788 orthologues and 5 paralogues. Restricted expression toward testis (RPKM 33.7).

Summary

This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014]

REG3G Products(3)

mRNA	Protein	Name
NM_001008387.3	NP_001008388.1	regenerating islet-derived protein 3-gamma isoform 1 preproprotein
NM_001270040.2	NP_001256969.1	regenerating islet-derived protein 3-gamma isoform 2 preproprotein
NM_198448.4	NP_940850.1	regenerating islet-derived protein 3-gamma isoform 1 preproprotein

REG3G Protein Structure

Lectin_C

0
100
175 a.a.

Protein Preferred Names

Protein Names

regenerating islet-derived protein 3-gamma

REG-3-gamma

Recombinant REG3G Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71255	REG-3 gamma/REG3G Protein, Human (HEK293, Fc)	Q6UW15 (E27-D175)	≥95%
HY-P71256	REG-3 gamma/REG3G Protein, Human (149a.a, HEK293, His)	Q6UW15 (E27-D175)	≥95%
HY-P76004	REG-3 gamma/REG3G Protein, Human (175a.a, HEK293, His)	Q6UW15 (M1-D175)	≥95%

Related Diseases

Diseases

Alias

Chemical Colitis

Pancreatitis

Mumps Pancreatitis

Alzheimer Disease 12

Ad12	Alzheimer'S Disease 12
Alzheimer Disease, Familial, 12	Alzheimer Disease Familial 12

X-Linked Immunodeficiency 74

Immunodeficiency 74, Covid-19-Related, X-Linked	Imd74
Respiratory Insufficiency Due To Sars-Cov-2 Viral Infection	Tlr7 Deficiency
X-Linked Immunodeficiency 74,Covid-19-Related

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11821	REG3G Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	REG3G	MGD	MGI:109406
Macaca mulatta	REG3G	VGNC	VGNC:106208
Rattus norvegicus	REG3G	RGD	RGD:3256
Others	REG3G	NCBI

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