PLEKHG4B - pleckstrin homology and RhoGEF domain containing G4B Gene

Homo sapiens

Gene ID: 153478 | Gene type: protein coding

About PLEKHG4B

This gene has 4 transcripts (splice variants), 144 orthologues and 22 paralogues. Biased expression in thyroid (RPKM 1.2), testis (RPKM 0.6) and 8 other tissues.

Summary

This gene encodes a large protein that contains a pleckstrin homology domain and may function as a guanine nucleotide exchange factor. [provided by RefSeq, May 2017]

PLEKHG4B Products(1)

mRNA	Protein	Name
NM_052909.5	NP_443141.4	pleckstrin homology domain-containing family G member 4B

PLEKHG4B Protein Structure

RhoGEF

0
200
400
600
800
1000
1200
1271 a.a.

Protein Preferred Names

Protein Names

pleckstrin homology domain-containing family G member 4B

PH domain-containing family G member 4B

Related Diseases

Diseases

Alias

Cri-Du-Chat Syndrome

5p Deletion Syndrome	5p Partial Monosomy Syndrome
Monosomy 5p	Cat Cry Syndrome
Chromosome 5p Deletion Syndrome	Cri Du Chat Syndrome
5p- Syndrome	5p Minus Syndrome
Chromosome 5p- Syndrome	Chromosome 5 Short Arm Deletion Syndrome
Chromosome 5p Deletion	Deletion 5p
Cri Du Chat	5p Partial Deletion Syndrome
Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10692	PLEKHG4B Human Pre-designed siRNA Set A		/	Unkown

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