1. Gene
  2. CLEC14A - C-type lectin domain containing 14A Gene

CLEC14A - C-type lectin domain containing 14A Gene

Homo sapiens

Also known as CEG1; EGFR-5; C14orf27

Gene ID: 161198 | Gene type: protein coding

About CLEC14A

Cytogenetic location: 14q21.1 Genomic coordinates (GRCh38): 14:38,254,000-38,256,093 (from NCBI)

This gene has 1 transcript (splice variant), 288 orthologues and 8 paralogues.

Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]

CLEC14A Products(1)

mRNA Protein Name
NM_175060.3 NP_778230.1 C-type lectin domain family 14 member A precursor
Protein Preferred Names Protein Names

C-type lectin domain family 14 member A

ClECT and EGF-like domain containing protein

Recombinant CLEC14A Proteins

Cat. No. Product Name Accession Purity
HY-P700693 CLEC14A Protein, Human (HEK293, His) Q86T13 (E22-A397) ≥95%

Orthologs Information

Species Symbol Source ID
Bos taurus CLEC14A VGNC VGNC:27425
Mus musculus CLEC14A MGD MGI:1914114
Macaca mulatta CLEC14A VGNC VGNC:108292
Rattus norvegicus CLEC14A RGD RGD:1306232
Canis familiaris CLEC14A VGNC VGNC:39327
Felis catus CLEC14A VGNC VGNC:60943
Others CLEC14A NCBI