RRP1B - ribosomal RNA processing 1B Gene

Homo sapiens

Also known as Nnp1; RRP1; NNP1L; KIAA0179; PPP1R136

Gene ID: 23076 | Gene type: protein coding

About RRP1B

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,659,560-43,696,079 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 10.6), testis (RPKM 10.3) and 25 other tissues.

Summary

Enables transcription coactivator activity. Involved in several processes, including cellular response to virus; positive regulation by host of viral transcription; and positive regulation of transcription by RNA polymerase II. Located in chromosome; granular component; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RRP1B Products(1)

mRNA	Protein	Name
NM_015056.3	NP_055871.1	ribosomal RNA processing protein 1 homolog B

RRP1B Protein Structure

Nop52

0
200
400
600
758 a.a.

Protein Preferred Names

Protein Names

ribosomal RNA processing protein 1 homolog B

RRP1-like protein B

Related Diseases

Diseases

Alias

Microinvasive Gastric Cancer

Early Gastric Cancer

Surface Gastric Cancer

Laryngeal Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Larynx	Squamous Cell Carcinoma Of Larynx
Squamous Cell Carcinoma Of The Larynx	Squamous Cell Carcinoma Of Head And Neck

Influenza

Flu	Influenza With Non-Respiratory Manifestation
Influenza With Other Manifestations	Influenza, Human
Influenza, Susceptibility To	Seasonal Influenza, Virus Identified

Osteogenesis Imperfecta, Type Xii

Osteogenesis Imperfecta Type 12	OI12
Osteogenesis Imperfecta Type Xii	Oi, Type Xii
Osteogenesis Imperfecta 12	Oi Type Xii
Oi-Xii	Osteogenesis Imperfecta Sillence Type Iii

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12291	RRP1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RRP1B	MGD	MGI:1919712
Canis familiaris	RRP1B	VGNC	VGNC:45766
Felis catus	RRP1B	VGNC	VGNC:64781
Macaca mulatta	RRP1B	VGNC	VGNC:77089
Rattus norvegicus	RRP1B	RGD	RGD:1305633
Bos taurus	RRP1B	VGNC	VGNC:34170

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