2. Gene
  3. ALKAL1 - ALK and LTK ligand 1 Gene

ALKAL1 - ALK and LTK ligand 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AUGA; AUGB; FAM150A; UNQ9433

Gene ID: 389658 | Gene type: protein coding

About ALKAL1

Cytogenetic location: 8q11.23 Genomic coordinates (GRCh38): 8:52,534,037-52,565,430 (from NCBI)

This gene has 2 transcripts (splice variants) and 161 orthologues. Biased expression in gall bladder (RPKM 1.3), thyroid (RPKM 1.1) and 7 other tissues.

Summary

Enables receptor signaling protein tyrosine kinase activator activity and receptor tyrosine kinase binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of ERK5 cascade; and positive regulation of neuron projection development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

ALKAL1 Products(1)

mRNA Protein Name
NM_207413.4 NP_997296.1 ALK and LTK ligand 1 precursor

ALKAL1 Protein Structure

FAM150

FAM150: FAM150 family (56 - 128)

  • 0
  • 100
  • 129 a.a.
Protein Preferred Names Protein Names

ALK and LTK ligand 1

AUG-beta

Recombinant ALKAL1 Proteins

Cat. No. Product Name Accession Purity
HY-P71584 ALKAL1 Protein, Human (His, B2M) Q6UXT8 (28R-129T) ≥95%

Related Diseases

Diseases Alias
Inflammatory Myofibroblastic Tumor

Inflammatory Fibrosarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00601 ALKAL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ALKAL1 VGNC VGNC:83979
Mus musculus ALKAL1 MGD MGI:3645495
Canis familiaris ALKAL1 VGNC VGNC:49887
Felis catus ALKAL1 VGNC VGNC:105869
Rattus norvegicus ALKAL1 RGD RGD:1583530
Others ALKAL1 NCBI