1. Gene
  2. LGALS8 - galectin 8 Gene

LGALS8 - galectin 8 Gene

Homo sapiens

Also known as Gal-8; PCTA1; PCTA-1; Po66-CBP

Gene ID: 3964 | Gene type: protein coding

About LGALS8

Cytogenetic location: 1q43 Genomic coordinates (GRCh38): 1:236,518,214-236,552,981 (from NCBI)

This gene has 28 transcripts (splice variants), 279 orthologues and 16 paralogues. Ubiquitous expression in spleen (RPKM 17.5), skin (RPKM 16.3) and 25 other tissues.

Summary

This gene encodes a member of the Galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, Apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

LGALS8 Products(4)

mRNA Protein Name
NM_006499.5 NP_006490.3 galectin-8 isoform a
NM_201543.4 NP_963837.1 galectin-8 isoform b
NM_201544.4 NP_963838.1 galectin-8 isoform b
NM_201545.2 NP_963839.1 galectin-8 isoform a

LGALS8 Protein Structure

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (18 - 150)

Gal-bind_lectin

Gal-bind_lectin: Galactoside-binding lectin (186 - 314)

  • 0
  • 100
  • 200
  • 317 a.a.
Protein Preferred Names Protein Names

galectin-8

Po66 carbohydrate binding protein

Recombinant LGALS8 Proteins

Cat. No. Product Name Accession Purity
HY-P70190 Galectin-8/LGALS8 Protein, Human O00214-1 (M1-W317) ≥95%
HY-P700081AF Animal-Free Galectin-8/LGALS8 Protein, Human (His) O00214-1 (M2-W317) ≥95%
HY-P700382 Galectin-8/LGALS8 Protein, Human (GST) O00214-1 (M1-W317) ≥95%

Related Diseases

Diseases Alias
Prostatic Hypertrophy

Benign Prostatic Hypertrophy

Prostatic Hyperplasia

Cholesteatoma Of Middle Ear

Cholesteatoma

Epidermosis Of Ear

Epidermosis Of Middle Ear

Middle Ear Cholesteatoma

Cholesteatoma Of Middle Ear And Mastoid

Cholesteatoma Of Middle Ear And/Or Mastoid

Cholesteatoma Of The Middle Ear

Congenital Cholesteatoma

Primary Acquired Cholesteatoma

Secondary Acquired Cholesteatoma

Cholesteatoma Middle Ear

Cholesteatoma, Middle Ear

Cholesterolosis Of Middle Ear

Cholesterosis Of Ear

Cholesterosis Of Middle Ear

Cholesteatoma Nos

Epidermoid Cholesteatoma

Middle Ear Granuloma

Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LGALS8 RGD RGD:621272
Macaca mulatta LGALS8 VGNC VGNC:74258
Canis familiaris LGALS8 VGNC VGNC:42650
Bos taurus LGALS8 VGNC VGNC:30855
Mus musculus LGALS8 MGD MGI:1928481
Others LGALS8 NCBI