TNFRSF19 - TNF receptor superfamily member 19 Gene

Homo sapiens

Also known as TAJ; TROY; TRADE; TAJ-alpha

Gene ID: 55504 | Gene type: protein coding

About TNFRSF19

Cytogenetic location: 13q12.12 Genomic coordinates (GRCh38): 13:23,570,412-23,676,093 (from NCBI)

This gene has 5 transcripts (splice variants), 209 orthologues and 2 paralogues. Biased expression in skin (RPKM 37.6), prostate (RPKM 12.9) and 8 other tissues.

Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing Apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

TNFRSF19 Products(5)

mRNA	Protein	Name
NM_001204458.3	NP_001191387.1	tumor necrosis factor receptor superfamily member 19 isoform 2 precursor
NM_001204459.2	NP_001191388.1	tumor necrosis factor receptor superfamily member 19 isoform 3
NM_001354985.2	NP_001341914.1	tumor necrosis factor receptor superfamily member 19 isoform 4 precursor
NM_018647.5	NP_061117.2	tumor necrosis factor receptor superfamily member 19 isoform 1 precursor
NM_148957.4	NP_683760.1	tumor necrosis factor receptor superfamily member 19 isoform 2 precursor

Protein Preferred Names

Protein Names

tumor necrosis factor receptor superfamily member 19

toxicity and JNK inducer

Recombinant TNFRSF19 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73572	TROY/TNFRSF19 Protein, Human (HEK293, His)	Q9NS68-2 (E30-L170)	≥95%
HY-P73573	TROY/TNFRSF19 Protein, Human (HEK293, Fc)	Q9NS68-2 (M1-L170)	≥95%

Related Diseases

Diseases

Alias

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Ectodermal Dysplasia

Congenital Ectodermal Defect	Congenital Ectodermal Dysplasia
Ectodermal Dysplasia Syndrome	Dysplasia, Ectodermal

Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive

Hypohidrotic Ectodermal Dysplasia	Hed
Anhidrotic Ectodermal Dysplasia	Ectodermal Dysplasia, Hypohidrotic
Eda	Christ-Siemens-Touraine Syndrome
ECTD10B	Ectodermal Dysplasia Anhidrotic
Ectodermal Dysplasia, Anhidrotic	Cst Syndrome
Ectodermal Dysplasia Hypohidrotic Autosomal Recessive	Dysplasia, Ectodermal, Type 10b, Hypohidrotic/Hair/Tooth, Autosomal Recessive
Dysplasia, Ectodermal, Hypohidrotic	Ectodermal Dysplasia 11b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive
Ectodermal Dysplasia 3, Anhidrotic	Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14809	TNFRSF19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TNFRSF19	MGD	MGI:1352474
Bos taurus	TNFRSF19	VGNC	VGNC:53840
Canis familiaris	TNFRSF19	VGNC	VGNC:47661
Felis catus	TNFRSF19	VGNC	VGNC:66407
Rattus norvegicus	TNFRSF19	RGD	RGD:1564996
Macaca mulatta	TNFRSF19	VGNC	VGNC:78588
Others	TNFRSF19	NCBI

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