CORO1B - coronin 1B Gene

Homo sapiens

Also known as CORONIN-2

Gene ID: 57175 | Gene type: protein coding

About CORO1B

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:67,435,510-67,443,809 (from NCBI)

This gene has 10 transcripts (splice variants), 200 orthologues and 6 paralogues. Ubiquitous expression in prostate (RPKM 38.7), spleen (RPKM 34.9) and 25 other tissues.

Summary

Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]

CORO1B Products(2)

mRNA	Protein	Name
NM_001018070.3	NP_001018080.1	coronin-1B
NM_020441.3	NP_065174.1	coronin-1B

CORO1B Protein Structure

DUF1899

WD40

Trimer_CC

0
100
200
300
400
489 a.a.

Protein Preferred Names

Protein Names

coronin-1B

coronin, actin binding protein, 1B

Related Diseases

Diseases

Alias

Coronin-1a Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03049	CORO1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CORO1B	MGD	MGI:1345963
Macaca mulatta	CORO1B	VGNC	VGNC:71320
Rattus norvegicus	CORO1B	RGD	RGD:2382
Bos taurus	CORO1B	VGNC	VGNC:27621
Felis catus	CORO1B	VGNC	VGNC:61102

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