PARD6B - par-6 family cell polarity regulator beta Gene

Homo sapiens

Also known as PAR6B

Gene ID: 84612 | Gene type: protein coding

About PARD6B

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:50,731,580-50,753,741 (from NCBI)

This gene has 2 transcripts (splice variants), 208 orthologues and 2 paralogues. Broad expression in kidney (RPKM 9.5), lung (RPKM 3.4) and 17 other tissues.

Summary

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]

PARD6B Products(1)

mRNA	Protein	Name
NM_032521.3	NP_115910.1	partitioning defective 6 homolog beta

PARD6B Protein Structure

PB1

PDZ

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

partitioning defective 6 homolog beta

PAR-6 beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10039	PARD6B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PARD6B	VGNC	VGNC:107850
Rattus norvegicus	PARD6B	RGD	RGD:1308205
Canis familiaris	PARD6B	VGNC	VGNC:54725
Bos taurus	PARD6B	VGNC	VGNC:32584
Mus musculus	PARD6B	MGD	MGI:2135605

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