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  2. RAB2B - RAB2B, member RAS oncogene family Gene

RAB2B - RAB2B, member RAS oncogene family Gene

Homo sapiens
Gene ID: 84932 | Gene type: protein coding

About RAB2B

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:21,459,020-21,476,959 (from NCBI)

This gene has 6 transcripts (splice variants), 114 orthologues and 68 paralogues. Ubiquitous expression in bone marrow (RPKM 6.9), testis (RPKM 6.8) and 25 other tissues.

Summary

Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]

RAB2B Products(2)

mRNA Protein Name
NM_001163380.2 NP_001156852.1 ras-related protein Rab-2B isoform 2
NM_032846.4 NP_116235.2 ras-related protein Rab-2B isoform 1

RAB2B Protein Structure

Ras

Ras: Ras family (8 - 168)

  • 0
  • 100
  • 200
  • 216 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-2B

GTP-binding protein RAB2B

Related Diseases

Diseases Alias
Carpenter Syndrome 1

Carpenter Syndrome

Acrocephalopolysyndactyly Type Ii

Acps Ii

CRPT1

Acrocephalopolysyndactyly Type 2

Acrocephalosyndactyly, Type Ii

Acrocephalopolysyndactyly 2

Acps2

Acps 2

Type Ii Acrocephalosyndactyly

Carpenter Syndrome, Type 1

Apert-Crouzon Disease

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus RAB2B MGD MGI:1923588
Macaca mulatta RAB2B VGNC VGNC:81530
Rattus norvegicus RAB2B RGD RGD:1309117
Bos taurus RAB2B VGNC VGNC:33638
Felis catus RAB2B VGNC VGNC:97588
Canis familiaris RAB2B VGNC VGNC:45272