STK17B - serine/threonine kinase 17b Gene

Homo sapiens

Also known as DRAK2

Gene ID: 9262 | Gene type: protein coding

About STK17B

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:196,133,583-196,176,483 (from NCBI)

This gene has 5 transcripts (splice variants), 202 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 54.0), lymph node (RPKM 45.0) and 18 other tissues.

Summary

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction; positive regulation of fibroblast apoptotic process; and protein phosphorylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

STK17B Products(1)

mRNA	Protein	Name
NM_004226.4	NP_004217.1	serine/threonine-protein kinase 17B

STK17B Protein Structure

Pkinase

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase 17B

DAP kinase-related apoptosis-inducing protein kinase 2

Related Diseases

Diseases

Alias

Colon Squamous Cell Carcinoma

Colonic Epidermoid Carcinoma	Squamous Cell Carcinoma Of Colon
Squamous Cell Carcinoma Of The Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Purity	Rare Diseases
HY-148062	RSS0680	98.03%	Unkown
HY-148063	DB0614	98.80%	Unkown
HY-156350	SGC-STK17B-1	/	Unkown
HY-RS13925	STK17B Human Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	STK17B	VGNC	VGNC:65778
Mus musculus	STK17B	MGD	MGI:2138162
Macaca mulatta	STK17B	VGNC	VGNC:110332
Rattus norvegicus	STK17B	RGD	RGD:620457
Canis familiaris	STK17B	VGNC	VGNC:46908
Bos taurus	STK17B	VGNC	VGNC:35388

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